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Epicardial FSTL1 reconstitution regenerates the adult mammalian heart
The elucidation of factors that activate the regeneration of the adult mammalian heart is of major scientific and therapeutic importance. Here we found that epicardial cells contain a potentExpand
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Cellular uptake of nanoparticles: journey inside the cell.
Nanoscale materials are increasingly found in consumer goods, electronics, and pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial and/or deleteriousExpand
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Engineered nanoparticles for biomolecular imaging.
In recent years, the production of nanoparticles (NPs) and exploration of their unusual properties have attracted the attention of physicists, chemists, biologists and engineers. Interest in NPsExpand
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Exocytosis of nanoparticles from cells: role in cellular retention and toxicity.
Over the past decade, nanoparticles (NPs) have been increasingly developed in various biomedical applications such as cell tracking, biosensing, contrast imaging, targeted drug delivery, and tissueExpand
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The effect of bioengineered acellular collagen patch on cardiac remodeling and ventricular function post myocardial infarction.
Regeneration of the damaged myocardium is one of the most challenging fronts in the field of tissue engineering due to the limited capacity of adult heart tissue to heal and to the mechanical andExpand
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Revisiting structure‐property relationship of pH‐responsive polymers for drug delivery applications
&NA; pH‐responsive polymers contain ionic functional groups as pendants in their structure. The total number of charged groups on polymer chains determines the overall response of the system toExpand
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Multiscale technologies for treatment of ischemic cardiomyopathy.
The adult mammalian heart possesses only limited capacity for innate regeneration and the response to severe injury is dominated by the formation of scar tissue. Current therapy to replace damagedExpand
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Patching up broken hearts: cardiac cell therapy gets a bioengineered boost.
Preclinical and clinical studies for cardiac cell therapy have only seen moderate success due to poor engraftment and survival of transplanted cells. In this issue of Cell Stem Cell, Ye et al. (2014)Expand
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Temperature: the "ignored" factor at the NanoBio interface.
Upon incorporation of nanoparticles (NPs) into the body, they are exposed to biological fluids, and their interaction with the dissolved biomolecules leads to the formation of the so-called proteinExpand
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[Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction.
Nanoparticle-mediated sustained delivery of therapeutics is one of the highly effective and increasingly utilized applications of nanomedicine. Here, we report the development and application of aExpand
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