Vadim Ratner

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Molecular mechanisms underlying programs of cell proliferation, differentiation and apoptosis are now under intensive investigation. Recent studies strongly suggest that triggering of these programs depends on the cell cycle control. Integrative approaches such as computer modeling are needed to analyze different modes of the complex dynamics of the(More)
The conflicting demands for simultaneous low-pass and high-pass processing, required in image denoising and enhancement, still present an outstanding challenge, although a great deal of progress has been made by means of adaptive diffusion-type algorithms. To further advance such processing methods and algorithms, we introduce a family of second-order (in(More)
It was recently shown that the brain-wide cerebrospinal fluid (CSF) and interstitial fluid exchange system designated the 'glymphatic pathway' plays a key role in removing waste products from the brain, similarly to the lymphatic system in other body organs(1,2). It is therefore important to study the flow patterns of glymphatic transport through the live(More)
It was recently shown that the brain-wide cerebrospinal fluid (CSF) and interstitial fluid exchange system designated the 'glymphatic pathway' plays a key role in removing waste products from the brain, similarly to the lymphatic system in other body organs 1,2. It is therefore important to study the flow patterns of glymphatic transport through the live(More)
Extracting nuclei is one of the most actively studied topic in the digital pathology researches. Most of the studies directly search the nuclei (or seeds for the nuclei) from the finest resolution available. While the richest information has been utilized by such approaches, it is sometimes difficult to address the heterogeneity of nuclei in different(More)
Segmentation of anatomical structures in medical imagery is a key step in a variety of clinical applications. Designing a generic, automated method that works for various structures and imaging modalities is a daunting task. Instead of proposing a new specific segmentation algorithm, in this paper, we present a general design principle on how to integrate(More)
We consider a coexistence of two axisymmetric liquid bridges LB i and LB m of two immiscible liquids i and m which are immersed in a third liquid (or gas) e and trapped between two smooth solid bodies with axisymmetric surfaces S 1 , S 2 and free contact lines. Evolution of liquid bridges allows two different configurations of LB i and LB m with multiple(More)