Vaclav Ruzicka

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Leptin receptors are supposed to have signal effects and are located in most tissues in the organism but we failed to find literary data on concentration (measurement) of leptin receptors in the system circulation. We examined by the method of randomized selection the group of 20 patients with manifested atherosclerosis in whom BMI was calculated. Then we(More)
Neurogenic contractions of a segment of myenteric plexus-longitudinal muscle strip preparations from the guinea-pig ileum were evoked. The site of electric stimulation was separated from the contracting segment by a gap preventing the spread of muscle action potentials set up in other regions. The width of the separating gap (2-20 mm) indicated the length(More)
Aim of study was determine if a correlation exists between bone mass density and concentration of osteoprotegerin. We examined the group of 199 patients of mean age of 63 years. Of the group under study, 31 patients had normal bone density (T score > -1 and < 1) and 168 probands had osteopenia or osteoporosis (T < -1). Persons with normal BMD values had(More)
The effect of tetanic stimulation on the twitch responses of the longitudinal muscle-myenteric plexus preparation of the guinea-pig ileum to electrical stimulation was investigated in the presence of naloxone. Under this condition, or after the addition of PGE2, twitch contractions were maximal and no potentiation of twitches following tetanus was observed.(More)
BACKGROUND Spontaneous splenic rupture (SSR) is a very rare complication described in several hundred patients, mainly as case reports. It is defined as a splenic rupture without antecedent injury. The authors of the present paper describe the only two SSR cases diagnosed at the Hemato-oncology department, coincidentally in one year. PATIENTS The first(More)
The supposed involvement of rat brain regions in the modulation of rat small intestine serotonergic activity was investigated. Small electrolytic lesions were placed in the areas of medulla oblongata and pons Varoli; one week later, changes in the serotonergic response of the intestine were detected. The contractions mediated by the activation of 5-HT2(More)
The authors observed in 60 human spleens the course of the splenic artery in the splenic hilus and branching of segmental branches in the spleen. Specimens of blood vessels and casts showed two extreme types of segmental branches entering the splenic parenchyma: 1. Vertical type and 2. subcapsular type. The authors also studied the occurrence of anastomoses(More)
Concentration-dependent 5-hydroxytryptamine (5-HT) relaxations of guinea pig proximal colon were evoked in the presence of atropine (0.2 microM). 5-HT effect was neuronally mediated since it was blocked by tetrodotoxin (TTX) (0.5 microM). The type of 5-HT receptor mediating the relaxations was investigated using both 5-HT agonists and antagonists. Selective(More)
The effect of tetanic stimulation on the twitch responses of the longitudinal muscle-myenteric plexus preparation of the guinea-pig ileum was investigated. In the presence of naloxone plus indomethacin twitch contractions following tetanus were potentiated. This posttetanic potentiation (PTP) of twitches was absent after reducing calcium concentration (0.6(More)
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