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Quantification of measles, mumps and rubella viruses using real-time quantitative TaqMan-based RT-PCR assay.
TLDR
The qPCR-RT assay was demonstrated to be a specific, sensitive, efficient and reproducible method, and could be used as an alternative method or a supplementary tool for the routine titer estimation during MMR vaccine production. Expand
[Comparative clinical trial of vaccines against avian influenza].
TLDR
Clinical trials of candidate vaccines against avian influenza concluded that both vaccines were safe, well tolerated and characterized by low reactogenicity, and researchers recommend it for clinical trials of 2nd phase. Expand
[Use of multiplex PCR method with real-time detection for differential diagnosis of respiratory viral infections].
TLDR
Results of tests for detection of IAV, IBV, RSV, PIV 1 - 4, and RV, analyzed by both systems, agreed in 94%. Expand
Synthesis and evaluation of novel lipopeptide as a vehicle for efficient gene delivery and gene silencing.
TLDR
It has been shown that the lipopeptide possesses low toxicity (in vitro and in vivo) and high transfection efficiency with pDNA and siRNA in different cell lines, and thus OrnOrnGlu(C16H33)2 is a promising vehicle for gene delivery and gene silencing. Expand
Vaccine Containing Natural TLR Ligands Protects from Salmonella typhimurium Infection in Mice and Acute Respiratory Infections in Children
TLDR
Repeated mucosal applications of this vaccine stimulated long-termprotection against acute respiratory infections in children of preschool age and short-term protection against lethal challenge with Salmonella typhimurium. Expand
The role of regulatory RNAs (miRNAs) in asthma.
TLDR
This work has shown that microRNAs play an important role in the regulation of many cellular processes and therefore can be potential targets for treatment in asthma. Expand
In vitro studies of the antiherpetic effect of photodynamic therapy
TLDR
PDT has been shown to be effective treatment for HVI in vitro, leading to a reliable decrease of viral titer, and had an antiviral effect on an in vitro model of H VI in cell culture. Expand
[Concept of inducing of rapid immunological protection against pathogens].
TLDR
Results of studies allowed to assume that activation of innate immunity mechanisms by preparations carrying pathogen-associated and molecular structures of microorganisms can result in formation of rapid and nonspecific protection against any pathogen. Expand
Immunosuppressive domains of retroviruses: Cell mechanisms of the effect on the human immune system
TLDR
The molecular aspects of the retroviral ISD-induced modulation of the host immune system are considered, including activation of signal transduction via the Ras-Raf-MEK-MAPK and PI3K-AKT-mTOR cell pathways as a result of the ISD interaction with immune cells. Expand
[Economic effectiveness of vaccination against rotavirus infection in the Russian Federation].
TLDR
Implementation of program of vaccination against rotavirus infection in the Russian Federation would promote the decrease of morbidity and economical efficiency and is 1.5 times less than the amount of expenses related to infection. Expand
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