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Insulin-dependent diabetes mellitus and menstrual dysfunction.
The consequences of IDDM on reproductive potential appear to be important and must be included in future investigative efforts, according to the prevailing views regarding the mechanisms through which uncontrolled IDDM is thought to disrupt normal hypothalamic-pituitary-gonadal function. Expand
Endometrin for luteal phase support in a randomized, controlled, open-label, prospective in-vitro fertilization trial using a combination of Menopur and Bravelle for controlled ovarian…
Pregnancy rates and live birth rates for Endometrin (twice daily and three times daily) were high and similar to those for P(4) gel and the adverse event profiles were similar across groups. Expand
Effects of Ultralow-Dose Transdermal Estradiol on Bone Mineral Density: A Randomized Clinical Trial
Postmenopausal treatment with low-dose, unopposed estradiol increased bone mineral density and decreased markers of bone turnover without causing endometrial hyperplasia. Expand
Progesterone pharmacokinetics and pharmacodynamics with 3 dosages and 2 regimens of an effervescent micronized progesterone vaginal insert.
The PVI system consistently allowed for rapid progesterone absorption and achieved higher endometrial tissue concentrations and lower systemic exposures than observed after im PIO. Expand
Mode of pulsatile follicle-stimulating hormone secretion in gonadal hormone-sufficient and -deficient women--a clinical research center study.
- R. A. Booth, J. Weltman, +7 authors W. Evans
- Biology, Medicine
- The Journal of clinical endocrinology and…
- 1 September 1996
It is suggested that FSH is secreted within discretesecretory bursts in women, that the mass and frequency of FSH secretory bursts differ in women exhibiting various gonadal hormone environments, and that F SHS and LH secretory burst occur coincidentally at a higher rate than expected on the basis of chance alone, but at such a low overall rate of concordance that distinct mechanisms probably operate to direct episodic FSH and LHsecretory activity. Expand
Endometrin® for Luteal Phase Support in a Randomized, Controlled, Open-Label, Prospective IVF Clinical Trial Using a Combination of Menopur® and Bravelle®
Randomized, assessor-blinded trial comparing highly purified human menotropin and recombinant follicle-stimulating hormone in high responders undergoing intracytoplasmic sperm injection.
In high responders, HP-hMG provided comparable efficacy to rFSH with fewer adverse events, including pregnancy loss, suggesting its optimized risk/benefit profile in this population. Expand
Highly purified human menotropin (HP-HMG) versus recombinant follicle stimulating hormone (RFSH) in high responders undergoing in vitro fertilization (IVF): MEGASET-HR trial outcomes
Can treatment of patients predicted to be high-responders be improved? insights from the menopur in GnRH antagonist single embryo transfer - high responder (MEGASET-HR) trial
Telmisartan Quality Control by Validation of UV-Spectrophotometric Method
- D. Tsvetkova, D. Obreshkova, S. Ivanova, V. Yankov, P. Atanasov, Bozhidarka Hadjieva
- Materials Science
- 25 May 2016
The aim of current study was to validate spectrophotometric method with UV-detection for identification and determination of Telmisartan in 99.8 % ethanol in respect of analytical parameters:… Expand