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Genome-wide analysis of the general stress response network in Escherichia coli: sigmaS-dependent genes, promoters, and sigma factor selectivity.
The sigmaS (or RpoS) subunit of RNA polymerase is the master regulator of the general stress response in Escherichia coli. While nearly absent in rapidly growing cells, sigmaS is strongly inducedExpand
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The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
The complete genomic sequence of Corynebacterium glutamicum ATCC 13032, well-known in industry for the production of amino acids, e.g. of L-glutamate and L-lysine was determined. The C. glutamicumExpand
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Nitrogen regulatory protein C-controlled genes of Escherichia coli: scavenging as a defense against nitrogen limitation.
Nitrogen regulatory protein C (NtrC) of enteric bacteria activates transcription of genes/operons whose products minimize the slowing of growth under nitrogen-limiting conditions. To reveal the NtrCExpand
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LrhA as a new transcriptional key regulator of flagella, motility and chemotaxis genes in Escherichia coli
The function of the LysR‐type regulator LrhA of Escherichia coli was defined by comparing whole‐genome mRNA profiles from wild‐type E. coli and an isogenic lrhA mutant on a DNA microarray. In theExpand
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Quantitative determination of metabolic fluxes during coutilization of two carbon sources: comparative analyses with Corynebacterium glutamicum during growth on acetate and/or glucose.
Growth of Corynebacterium glutamicum on mixtures of the carbon sources glucose and acetate is shown to be distinct from growth on either substrate alone. The organism showed nondiauxic growth onExpand
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The DeoR-type regulator SugR represses expression of ptsG in Corynebacterium glutamicum.
Corynebacterium glutamicum grows on a variety of carbohydrates and organic acids. Uptake of the preferred carbon source glucose via the phosphoenolpyruvate-dependent phosphotransferase system (PTS)Expand
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Amino acid biosynthesis : pathways, regulation and metabolic engineering
Production of Glutamate and Glutamate-Related Amino Acids: Molecular Mechanism Analysis and Metabolic Engineering.- The l-Lysine Story: From Metabolic Pathways to Industrial Production.-Expand
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Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria
Escherichia coli grew in a minimal medium on propionate as the sole carbon and energy source. Initially a lag phase of 4–7 days was observed. Cells adapted to propionate still required 1–2 daysExpand
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Characterization of a Corynebacterium glutamicum Lactate Utilization Operon Induced during Temperature-Triggered Glutamate Production
ABSTRACT Gene expression changes of glutamate-producing Corynebacterium glutamicum were identified in transcriptome comparisons by DNA microarray analysis. During glutamate production induced by aExpand
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Corynebacterium glutamicum Tailored for Efficient Isobutanol Production †
ABSTRACT We recently engineered Corynebacterium glutamicum for aerobic production of 2-ketoisovalerate by inactivation of the pyruvate dehydrogenase complex, pyruvate:quinone oxidoreductase,Expand
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