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Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting.
TLDR
A complete pathway for the rare and potent antitumor agent psymberin from Psammocinia aff.
Rossinones A and B, biologically active meroterpenoids from the Antarctic ascidian, Aplidium species.
TLDR
Rossinones A and B, biologically active meroterpene derivatives, were isolated from an Antarctic collection of the ascidian Aplidium species and structurally characterized with spectroscopic methods and exhibit anti-inflammatory, antiviral and antiproliferative activities.
E/Z-rubrolide O, an anti-inflammatory halogenated furanone from the New Zealand ascidian Synoicum n. sp.
Bioassay-directed fractionation of extracts of a Synoicum n. sp. ascidian from New Zealand led to the isolation of the principal anti-inflammatory component, which was identified by spectroscopic
Sequence analysis of 16S rRNA gene of cyanobacteria associated with the marine sponge Mycale (Carmia) hentscheli.
TLDR
The phylogenetic analysis indicated the presence of four closely related clones which have a high sequence divergence from known cyanobacteria, Cyanobacterium stanieri being the closest, followed by Prochloron sp.
Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis.
TLDR
Two new tricyclic thiazine-containing quinolinequinone alkaloids were isolated from the New Zealand ascidian Aplidium species and inhibited the in vitro production of superoxide by PMA-stimulated human neutrophils in a dose-dependent manner.
Enantiomeric discorhabdin alkaloids and establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra.
TLDR
Enantiomeric pairs of the cytotoxic pyrroloiminoquinone marine alkaloids discorhabdins have been isolated from Latrunculia species sponges collected around the coast of New Zealand and exhibit equipotent antiproliferative biological activity.
Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum.
Bioassay-directed fractionation of an extract of the New Zealand ascidian Aplidium scabellum has afforded the anti-inflammatory secondary metabolite 2-geranyl-6-methoxy-1,4-hydroquinone-4-sulfate (1)
An antiproliferative bis-prenylated quinone from the New Zealand brown alga Perithalia capillaris.
TLDR
This report extends the examples of bis-prenylated phenols as chemotaxonomic markers for brown algae of the order Sporochnales to include New Zealand brown alga Perithalia capillaris.
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