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- Publications
- Influence
Endothelial Progenitors: A Consensus Statement on Nomenclature
- Reinhold J Medina, C. Barber, +10 authors Alan W. Stitt
- Biology, Medicine
- Stem cells translational medicine
- 10 March 2017
Endothelial progenitor cell (EPC) nomenclature remains ambiguous and there is a general lack of concordance in the stem cell field with many distinct cell subtypes continually grouped under the term… Expand
Matrix Metalloproteinase-8 Is Expressed in Rheumatoid Synovial Fibroblasts and Endothelial Cells
- R. Hanemaaijer, T. Sorsa, +9 authors T. Salo
- Chemistry, Materials Science
- The Journal of Biological Chemistry
- 12 December 1997
Neutrophil collagenase (matrix metalloproteinase-8 or MMP-8) is regarded as being synthesized exclusively by polymorphonuclear neutrophils (PMN). However, in vivo MMP-8 expression was observed in… Expand
Endothelial dysfunction and pathogenesis of diabetic angiopathy.
- C. Stehouwer, J. Lambert, A. J. Donker, V. W. V. van Hinsbergh
- Medicine
- Cardiovascular research
- 1 April 1997
OBJECTIVE AND METHODS
To review, from the clinical perspective, the contribution of dysfunction of the vascular endothelium to the pathogenesis of diabetic micro- and macroangiopathy.
RESULTS… Expand
Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for…
- H. G. Blaauwgeers, G. Holtkamp, +8 authors R. Schlingemann
- Biology, Medicine
- The American journal of pathology
- 1 August 1999
The retinal pigment epithelium (RPE) maintains the choriocapillaris (CC) in the normal eye and is involved in the pathogenesis of choroidal neovascularization in age-related macular degeneration.… Expand
Involvement of RhoA/Rho Kinase Signaling in VEGF-Induced Endothelial Cell Migration and Angiogenesis In Vitro
- G. P. van Nieuw Amerongen, P. Koolwijk, Amanda Versteilen, V. W. V. van Hinsbergh
- Biology, Medicine
- Arteriosclerosis, thrombosis, and vascular…
- 1 February 2003
Objective—Growth factor-induced angiogenesis involves migration of endothelial cells (ECs) into perivascular areas and requires active remodeling of the endothelial F-actin cytoskeleton. The small… Expand
Inhibition of MMP Synthesis by Doxycycline and Chemically Modified Tetracyclines (CMTs) in Human Endothelial Cells
- R. Hanemaaijer, H. Visser, +4 authors V. W. V. van Hinsbergh
- Biology, Medicine
- Advances in dental research
- 1 November 1998
Doxycycline is a commonly used broad-spectrum antibiotic. Recently, it has been shown that it also inhibits the activity of mammalian collagenases and gelatinases, an activity unrelated to its… Expand
Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces.
- R. Krishnan, D. Klumpers, +9 authors G. P. van Nieuw Amerongen
- Biology, Medicine
- American journal of physiology. Cell physiology
- 2011
A hallmark of many, sometimes life-threatening, inflammatory diseases and disorders is vascular leakage. The extent and severity of vascular leakage is broadly mediated by the integrity of the… Expand
Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus.
- M. Bourajjaj, C. Stehouwer, V. W. V. van Hinsbergh, C. Schalkwijk
- Chemistry, Medicine
- Biochemical Society transactions
- 1 December 2003
Various theories have been proposed to explain the hyperglycaemia-induced pathogenesis of vascular complications of diabetes, including detrimental effects of AGEs (advanced glycation end products)… Expand
Microtubule-targeting agents inhibit angiogenesis at subtoxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton
- M. N. Bijman, G. P. van Nieuw Amerongen, N. Laurens, V. W. V. van Hinsbergh, E. Boven
- Biology, Medicine
- Molecular Cancer Therapeutics
- 1 September 2006
Conventional anticancer agents may display antiangiogenic effects, but the underlying mechanism is poorly understood. We determined the antiangiogenic properties of cisplatin, doxorubicin, and the… Expand
von Willebrand factor, C-reactive protein, and 5-year mortality in diabetic and nondiabetic subjects: the Hoorn Study.
- A. Jager, V. W. V. van Hinsbergh, +7 authors C. Stehouwer
- Medicine
- Arteriosclerosis, thrombosis, and vascular…
- 1 December 1999
Increased levels of von Willebrand factor (vWf) and C-reactive protein (CRP) predict cardiovascular mortality in selected populations. It is uncertain whether vWf and CRP predict mortality in a… Expand