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Extensive MHC variability in cichlid fishes of Lake Malawi
LAKE Malawi in East Africa harbours 500–1,000 endemic species of cichlid fishes, all presumably derived by adaptive radiation from a single founding population within the past two million years1–3.Expand
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Linkage relationships and haplotype polymorphism among cichlid Mhc class II B loci.
The species flocks of cichlid fishes in the Great East African Lakes are paradigms of adaptive radiation and hence, of great interest to evolutionary biologists. Phylogenetic studies of these fishesExpand
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A Tissue Fixative that Protects Macromolecules (DNA, RNA, and Protein) and Histomorphology in Clinical Samples
Preservation of macromolecules (DNA, RNA, and proteins) in tissue is traditionally achieved by immediate freezing of the sample. Although isolation of PCR-able RNA has been reported fromExpand
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Major histocompatibility complex class II genes of zebrafish.
  • H. Ono, D. Klein, +4 authors J. Klein
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 15 December 1992
Twenty cDNA clones derived from beta-chain-encoding class II genes of the zebrafish (Brachydanio rerio) major histocompatibility complex (MHC) have been sequenced. They fall into three groupsExpand
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Molecular characterization of a urea transporter in the gill of the gulf toadfish (Opsanus beta).
Urea excretion by the gulf toadfish (Opsanus beta) has been shown in previous studies to be a highly pulsatile facilitated transport, with excretion probably occurring at the gill. The present studyExpand
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Immune surveillance and sunlight-induced skin cancer.
Immune surveillance poses the existence of a recirculating pool of lymphocytes that migrate randomly through somatic tissues. Upon recognition of neoantigens on malignantly transformed cells,Expand
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Cloning and characterization of a 70 kd heat shock cognate (hsc70) gene from the zebrafish (Danio rerio)
The heat shock 70 family of proteins is one of the most highly conserved among all species. The genes encoding these proteins have been cloned and sequenced from bacterial species to humans with aExpand
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Linkage map of mouse chromosome 17: localization of 27 new DNA markers.
Chromosome 17 of the laboratory variant of the house mouse (Mus musculus L.), MMU17, has been studied extensively, largely because of its involvement in the control of immune response and embryonicExpand
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Characterization and sequencing of glutamine synthetase cDNA from liver of the ureotelic gulf toadfish (Opsanus beta).
The hepatic enzyme, glutamine synthetase (GSase) is a pivotal protein in the regulation of urea synthesis in fish. The sequence of the DNA encoding for GSase from liver of the ureotelic gulf toadfishExpand
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Relationship between ultraviolet radiation-induced immunosuppression and carcinogenesis.
The capacity of ultraviolet B (UVB) radiation to damage the cutaneous immune system has been extensively documented, and there is good reason to believe that UVB-induced damage is a critical, albeitExpand
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