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An endophytic fungus from Nothapodytes foetida that produces camptothecin.
- S. Puri, V. Verma, T. Amna, G. N. Qazi, M. Spiteller
- BiologyJournal of natural products
- 12 November 2005
Isolation of an organism producing camptothecin and its fermentation may, in the future, provide an easily accessible source for the production of this anticancer drug precursor molecule.
The endophytic fungus Trametes hirsuta as a novel alternative source of podophyllotoxin and related aryl tetralin lignans.
Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus
- I. Khan, Zahid Mehmood Mirza, Ashwani Kumar, V. Verma, G. N. Qazi
- BiologyAntimicrobial Agents and Chemotherapy
- 1 February 2006
The enhanced accumulation and decreased efflux of ethidium bromide in the wild-type and mutant (CIPr-1) strains in the presence of piperine suggest its involvement in the inhibition of bacterial efflux pumps.
Purification and characterization of peroxidases from Withania somnifera (AGB 002) and their ability to oxidize IAA
Isolation and identification of an endophytic strain of Fusarium oxysporum producing podophyllotoxin from Juniperus recurva
First time the production of podophyllotoxin by an endophytic fungus Fusarium oxysporum isolated from the medicinal plant Juniperus recurva is reported.
Phytochemical and genetic analysis in selected chemotypes of Withania somnifera.
Withanolide production by in vitro cultures of Withania somnifera and its association with differentiation
Results suggest that production of withanolides is closely associated with morphological differentiation in plants cultured in vitro at different developmental phases.
Bioreactor studies on the endophytic fungus Entrophospora infrequens for the production of an anticancer alkaloid camptothecin.
One of the isolates from the inner bark tissue of the N. foetida plant growing in the Jammu region of J&K state, India, was found to produce detectable quantities of camptothecin and its derivatives when grown in a semi-synthetic liquid medium.
An endophytic Neurospora sp. from Nothapodytes foetida producing camptothecin
- S. Rehman, A. S. Shawl, G. N. Qazi
- Biology, ChemistryApplied Biochemistry and Microbiology
- 1 March 2008
Isolated endophyte (Neurospora crassa) producing camptothecin may become an easily accessible source for the production of a precursor anticancer drug molecule in the future at a large scale.