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Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus.
BACKGROUND The efficacy of conventional treatment with surgery and radiation for cancer of the esophagus is limited. The median survival is less than 10 months, and less than 10 percent of patientsExpand
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Combined therapy for cancer of the anal canal: A preliminary report
IN COMPARISON with adenocarcinoma of the rectum, anal cancer is uncommon. 2 According to Morson, a one squamous-cell cancer is seen for every 28 rectal adenocarcinomas, an incidence of about .'4.5Expand
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Progress report of combined chemoradiotherapy versus radiotherapy alone in patients with esophageal cancer: an intergroup study.
PURPOSE The present intergroup phase III randomized study compared combined chemotherapy (CT) plus radiotherapy (RT) treatment versus RT only in patients with locally advanced esophageal cancer. Expand
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Malignant melanoma and central nervous system metastases. Incidence, diagnosis, treatment and survival
One hundred and twenty‐two patients with clinically advanced, histologically confirmed, cutaneous malignant melanoma, seen at Wayne State University over a 12 year period were reviewed. The incidenceExpand
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Comparison of continuously infused 5‐fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma
In a randomized series of 70 patients with with colo rectal adenocarcinoma, a comparison of systemic 5‐fluorouracil chemotherapy administered as a continuous 120‐hours infusion vs. intravenous bolusExpand
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Intensity-modulated radiotherapy (IMRT) and concurrent capecitabine for pancreatic cancer.
PURPOSE Local failure continues to be a major problem in the management of pancreatic cancer. Delivery of adequate radiation doses to the pancreas is limited by radiation-sensitive normal structuresExpand
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Combined preoperative radiation and chemotherapy for squamous cell carcinoma of the anal canal
Twenty‐eight patients with squamous cell carcinoma of the anal canal were treated by preoperative radiation therapy and chemotherapy. The radiation therapy was given for 3000 rad (30 Gy) at 200 radExpand
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Foamy gland pattern of pancreatic ductal adenocarcinoma: a deceptively benign-appearing variant.
Pathologic diagnosis of pancreatic adenocarcinoma is frequently a challenge, particularly in small biopsies, frozen sections, and in metastatic foci. Here we report a deceptively benign-appearing andExpand
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Pharmacokinetics of 5-fluorouracil administered orally, by rapid intravenous and by slow infusion.
Pharmacokinetic studies of 5-fluorouracil (5-FUra) were performed on 18 patients divided into three groups: seven patients were given 5-FUra i.v. by rapid injection; five patients received the drugExpand
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Clinical presentation, natural history and prognostic factors in advanced malignant melanoma.
A retrospective study of the clinical findings and natural history of 140 patients with disseminated malignant melanoma treated at Wayne State University over a ten year period was done. MultipleExpand
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