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Transit through the Flea Vector Induces a Pretransmission Innate Immunity Resistance Phenotype in Yersinia pestis
It is suggested that transit through the flea vector induces a phenotype that enhances survival and dissemination of Y. pestis after transmission to the mammalian host. Expand
Role of the luxS Quorum-Sensing System in Biofilm Formation and Virulence of Staphylococcus epidermidis
A general scheme of quorum-sensing regulation of biofilm development in staphylococci, which contrasts with that observed in many other bacterial pathogens, is indicated. Expand
Membranes of Class IIa Bacteriocin-Resistant Listeria monocytogenes Cells Contain Increased Levels of Desaturated and Short-Acyl-Chain Phosphatidylglycerols
It appears that membrane adaptation may be part of a resistance mechanism but that several resistance mechanisms may contribute to a resistance phenotype and that levels of resistance vary according to the type of mechanisms present. Expand
Cell-surface alterations in class IIa bacteriocin-resistant Listeria monocytogenes strains.
A clear correlation between d-alanine content in teichoic acid (TA), in particular the alanine : phosphorus ratio, and a more positive cell surface, as determined by cytochrome c binding, were found for the highly resistant strains, indicating that all these factors could contribute to class IIa bacteriocin resistance. Expand
Mechanisms of post-transcriptional gene regulation in bacterial biofilms
Post-transcriptional regulation is a powerful molecular mechanism employed by bacteria to rapidly adjust to the changing environment and to fine tune gene expression to the developmental needs of the cell. Expand
AI-2-dependent gene regulation in Staphylococcus epidermidis
The results provide a detailed molecular basis for the role of LuxS in S. epidermidis virulence and suggest a signaling function for AI-2 in this bacterium. Expand
Hfq Regulates Biofilm Gut Blockage That Facilitates Flea-Borne Transmission of Yersinia pestis
Hfq is revealed to be essential for biofilm blockage formation and acquisition and fitness of Y. pestis during flea gut infection, consistent with posttranscriptional regulatory mechanisms in plague transmission. Expand
Acute oral toxicity of Yersinia pseudotuberculosis to fleas: implications for the evolution of vector‐borne transmission of plague
It is found that loss of one or more insect gut toxins was a critical step in the recent evolution of flea‐borne transmission in the genus Yersinia, and changes in the tc insecticidal genes do not appear to have been responsible, but may have had other effects on Yerinia–flea interactions. Expand
Molecular Genetics of Staphylococcus Epidermidis Biofilms on Indwelling Medical Devices
  • V. Vadyvaloo, M. Otto
  • Biology, Medicine
  • The International journal of artificial organs
  • 1 November 2005
Biofilm formation is a major problem in treating S. epidermidis infection as biofilms provide significant resistance to antibiotics and to components of the innate host defenses. Expand
Conservation of residues involved in sugar/H(+) symport by the sucrose permease of Escherichia coli relative to lactose permease.
Functional analyses of mutants in the homologous key residues provide strong evidence that they play a similar critical role in the mechanisms of CscB and LacY. Expand