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Stability evaluation and sensitive determination of antiviral drug, valacyclovir and its metabolite acyclovir in human plasma by a rapid liquid chromatography-tandem mass spectrometry method.
A simple, sensitive and high throughput liquid chromatography/positive-ion electrospray ionization mass spectrometry (LC-ESI-MS/MS) method has been developed for the simultaneous determination ofExpand
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Biochemistry of Cheese Ripening: Proteolysis
Abstract The enzymatic hydrolysis of the casein matrix is a major biochemical event that occurs during cheese ripening. Products of proteolysis are a very large number of peptides, together with freeExpand
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Comparison of extraction procedures for assessment of matrix effect for selective and reliable determination of atazanavir in human plasma by LC-ESI-MS/MS.
A comparative study with three conventional extraction techniques namely protein precipitation (PP), liquid-liquid extraction (LLE) and solid phase extraction (SPE) has been demonstrated to assessExpand
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Determination of mycophenolic acid in human plasma by ultra performance liquid chromatography tandem mass spectrometry
A simple, sensitive and high throughput ultra performance liquid chromatography tandem mass spectrometry method has been developed for the determination of mycophenolic acid in human plasma. TheExpand
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Automated liquid-liquid extraction based on 96-well plate format in conjunction with ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) for the quantitation of methoxsalen
A sensitive, specific and high throughput bioanalytical method using automated sample processing via 96-well plate liquid-liquid extraction and ultra-performance liquid chromatography tandem massExpand
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Impact of electrospray ion source platforms on matrix effect due to plasma phospholipids in the determination of rivastigmine by LC-MS/MS.
BACKGROUND This study evaluates the performance of three electrospray ionization source designs to monitor the interference of plasma phospholipids for reliable estimation of rivastigmine by LC-MS/MSExpand
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Effects of high pressure on some constituents and properties of buffalo milk.
In this study, effects of high pressure (HP) on some constituents and properties of buffalo milk were examined. HP treatment at 100-600MPa for 30 min affected casein micelle size only slightly,Expand
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Polymerization of 1,3‐butadiene using neodymium chloride tripentanolate–triethyl aluminum catalyst systems
Neodymium chloride tripentanolate catalysts of the general formula NdCl3 × nL with n = 3, L = 1-pentanol (II), 2-pentanol (III), and 3-pentanol (IV) were prepared by an alcohol interchange reactionExpand
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A Mathematical Model on the Two Phase Renal Systolic Blood Flow in Renal Arterioles with Special Reference to Kidney Infection ( UTI )
In the present paper we have formulated the renal Systolic blood flow in arteries. Keeping in view the nature of renal circulatory system in human body. The viscosity increases in the arterioles dueExpand
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Quantitation of Sirolimus in Human Whole Blood by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry for a Bioequivalence Study
A sensitive and high throughput ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method has been developed for the determination of sirolimus in human whole blood. TheExpand