• Publications
  • Influence
Identification of natural compounds which inhibit biofilm formation in clinical isolates of Klebsiella pneumoniae.
Klebsiella pneumoniae, an important opportunistic pathogen, exists as a biofilm in persistent infections and in-dwelling medical devices. With the objective of identifying natural compoundsExpand
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Cellular chemosensitivity assays: an overview.
  • V. Sumantran
  • Chemistry, Medicine
  • Methods in molecular biology
  • 2011
Data on cell viability have long been obtained from in vitro cytotoxicity assays. Today, there is a focus on markers of cell death, and the MTT cell survival assay is widely used for measuringExpand
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Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial.
OBJECTIVE To demonstrate clinical equivalence between two standardized Ayurveda (India) formulations (SGCG and SGC), glucosamine and celecoxib (NSAID). METHODS Ayurvedic formulations (extracts ofExpand
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Cancer, Inflammation, and Insights from Ayurveda
A recent, exciting discovery relates to the concept of “shared pathology” between cancer and metabolic syndrome. One major pathway common to cancer and metabolic syndrome is chronic inflammation,Expand
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Hyaluronidase and collagenase inhibitory activities of the herbal formulation Triphala guggulu
Myrrh (guggulu) oleoresin from the Commiphora mukul tree is an important component of antiarthritic drugs in Ayurvedic medicine. Clinical data suggest that elevated levels of hyaluronidase andExpand
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Expression of High Mobility Group A2 Protein in Retinoblastoma and its Association With Clinicopathologic Features
Retinoblastoma (RB) is the commonest primary intraocular tumor in children. Overexpression of the high mobility group (HMG) A2 protein has been observed in a variety of malignant tumors and oftenExpand
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Neuroblastoma‐specific cytotoxicity mediated by the Mash1‐promoter and E. coli purine nucleoside phosphorylase
Neuroblastoma is derived from cells of neural crest origin and often expresses the transcription factor human achaete‐scute homolog 1 (HASH1). The aim of this study was to selectively killExpand
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Antiarthritic Activity of a Standardized, Multiherbal, Ayurvedic Formulation containing Boswellia serrata: In Vitro Studies on Knee Cartilage from Osteoarthritis Patients
A validated in vitro model of cartilage damage and published data were used showing that this model measures the chondroprotective and antiinflammatory effects of different antiarthritic drugs. InExpand
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Chondroprotective potential of root extracts of Withania somnifera in osteoarthritis
This is the first report describing two novel chondroprotective activities of aqueous extracts of Withania somnifera root powder. First, these extracts had a statistically significant, short-termExpand
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The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro
Using a validated explant model of in vitro cartilage damage, the effects of aqueous extracts of Withania somnifera (Ashwagandha) root and glucosamine sulphate (GlcS) were tested on the levels ofExpand
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