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Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors
Flavonoids have recently aroused considerable interest because of their broad pharmacological activity. In fact, flavonoids have been reported to have antiviral, antiallergic, antiplatelet,Expand
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L-Propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector
L-Propionylcarnitine, a propionyl ester of L-carnitine, increases the intracellular pool of L-carnitine. It exhibits a high affinity for the enzyme carnitine acetyltransferase (CAT) and, thus, isExpand
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Toxicity of Ochratoxin A and Its Modulation by Antioxidants: A Review
Ochratoxin A (OTA) is a mycotoxin involved in the development of different types of cancers in rats, mice and humans. A growing number of in vitro and in vivo studies has been collected and hasExpand
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Progress in the development of selective nitric oxide synthase (NOS) inhibitors.
Nitric oxide (NO), a molecular messenger synthesized by nitric oxide synthase (NOS) from L-arginine and molecular oxygen, is involved in a number of physiological and pathological processes inExpand
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High glucose-mediated imbalance of nitric oxide synthase and dimethylarginine dimethylaminohydrolase expression in endothelial cells.
The mechanisms involved in endothelial dysfunction are multifactorial. A correlation between oxidative stress and derangements of nitric oxide synthase (NOS) pathways in altered endothelialExpand
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Antiproliferative effect of oleuropein in prostate cell lines.
Currently, there is increasing interest in the in vivo protective effects of natural antioxidants found in dietary plants against oxidative damage caused by free radical species. Oxidative stress hasExpand
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Cyanidin induces apoptosis and differentiation in prostate cancer cells.
Several natural antioxidants, including anthocyanins, have been reported to have chemotherapeutic activity in vivo and in vitro. The aim of the present study was to delineate the anti-proliferativeExpand
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Effect of Ischemia–Reperfusion on Renal Expression and Activity of NG-NG-Dimethylarginine Dimethylaminohydrolases
Background:Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase. It is degraded by the enzyme dimethylarginine dimethylaminohydrolase (DDAH). Methods:Rats (n = 50)Expand
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Expression of bone morphogenetic protein-6 and transforming growth factor-β1 in the rat brain after a mild and reversible ischemic damage
We have examined the distribution of transforming growth factor-beta1 (TGF-beta1) and bone morphogenetic protein-6 (BMP-6) in the brain of rats subjected to a mild and reversible ischemic damageExpand
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Heme oxygenase induction by cyanidin-3-O-beta-glucoside in cultured human endothelial cells.
The aim of the present research was to investigate the effect of cyanidin-3-O-beta-glucoside (C3G) on heme oxygenase-1 (HO-1), endothelial nitric oxide synthase (eNOS), inducible NOS (iNOS) andExpand
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