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Cutaneous leishmaniasis caused by Leishmania infantum transmitted by Phlebotomus tobbi.
TLDR
Transmission of cutaneous leishmaniasis (CL) caused by Leishmania infantum was studied in South Anatolia, Turkey and it is suggested that the transmission cycle could be anthroponotic. Expand
Spread of the West Nile virus vector Culex modestus and the potential malaria vector Anopheles hyrcanus in central Europe
TLDR
The findings reveal that the mosquito fauna is enriched by new elements in the Mediterranean region and suggests that the newly-emerging potential malaria vector, Anopheles hyrcanus, has reached the northern limit of its distribution in the Czech Republic, and the important West Nile virus (WNV) vector has widened its distribution. Expand
Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression
TLDR
The whole genomes and transcriptomes of Leishmania donovani strains throughout their adaptation to in vivo conditions mimicking natural vertebrate and invertebrate host environments are sequenced to allow studies of the impact of aneuploidy on molecular adaptations and cellular fitness. Expand
Experimental Transmission of Leishmania infantum by Two Major Vectors: A Comparison between a Viscerotropic and a Dermotropic Strain
TLDR
The maximal natural dose found was still about 250 times lower than the experimental challenge dose used in previous studies, which emphasizes the importance of determining the natural infective dose for the development of an accurate experimental model useful for the evaluation of new drugs and vaccines. Expand
Visualisation of Leishmania donovani Fluorescent Hybrids during Early Stage Development in the Sand Fly Vector
Background The Leishmania protozoan parasites cause devastating human diseases. Leishmania have been considered to replicate clonally, without genetic exchange. However, an accumulation of evidenceExpand
Quantifying the Contribution of Hosts with Different Parasite Concentrations to the Transmission of Visceral Leishmaniasis in Ethiopia
TLDR
A novel mechanistic model is developed that facilitates the quantification of the contribution of hosts with different parasitemia to the infection of the vectors from data on the distribution of these parasitemias within the host population. Expand
Sergentomyia schwetzi is not a competent vector for Leishmania donovani and other Leishmania species pathogenic to humans
TLDR
Sergentomyia schwetzi is refractory to human Leishmania species and the data indicate that the crucial aspect of the refractoriness is the relative timing of defecation versus PM degradation. Expand
Comparison of Bloodmeal Digestion and the Peritrophic Matrix in Four Sand Fly Species Differing in Susceptibility to Leishmania donovani
TLDR
It is hypothesised that the period between the breakdown of the PM and defecation of the bloodmeal remnants, could be one of crucial parameters responsible for the establishment of Leishmania in the sand fly midgut. Expand
Leishmania major Glycosylation Mutants Require Phosphoglycans (lpg2 −) but Not Lipophosphoglycan (lpg1 −) for Survival in Permissive Sand Fly Vectors
TLDR
The data establish clearly that LPG is not required for Leishmania survival in permissive species P. perniciosus and P. argentipes, and the data prove the importance of LPG2-related molecules for survival of L. major in the three sand fly species tested. Expand
The Biting Midge Culicoides sonorensis (Diptera: Ceratopogonidae) Is Capable of Developing Late Stage Infections of Leishmania enriettii
TLDR
The hypothesis that some biting midges could be natural vectors of the L. enriettii complex because of their vector competence is supported, although not Culicoides sonorensis itself, which is not sympatric; midges should be assessed in the field while searching for vectors of related Leishmania species including L. martiniquensis and "L. siamensis". Expand
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