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MYD88 L265P Mutation Is a Possible Unfavorable Prognostic Factor in Patients with Diffuse B-Cell Lymphoma
TLDR
IPI high risk and extranodal involvement is common in ABC DLBCL pts with MYD88 L265P mutation, and this mutation can be a predisposing factor for poor OS probability in pts with ABCDLBCL. Expand
[Allogenic bone marrow transplantation in chronic myeloid leukemias].
TLDR
The experience of many years demonstrates high efficacy of ABM transplantation in the treatment of chronic myeloid leukemia, which promotes long-term molecular remission the maintenance of which did not require therapy in 65% patients. Expand
Recovery of Donor Hematopoiesis after Graft Failure and Second Hematopoietic Stem Cell Transplantation with Intraosseous Administration of Mesenchymal Stromal Cells
TLDR
It is suggested that MSCs could participate in the restoration of niches for donor hematopoietic cells or have an immunomodulatory effect, preventing repeated rejection of the graft. Expand
Two novel HLA alleles identified in Russian bone marrow donors: HLA‐A*02:957 and ‐C*12:03:67
TLDR
Characterization of two novel HLA class I alleles, A*02:957 and C*12-03:67, shows good correspondence with known HLA classes II and III alleles. Expand
HLA‐A*24:521 and HLA‐B*13:152 identified by next‐generation sequencing in Russian bone marrow donors
TLDR
Two novel alleles, HLA•A*24:521 and HLA‐B*13:152, are characterized and it is confirmed that these alleles are related to Huntington's disease and central nervous system disease. Expand
[Molecular cytogenetic monitoring of chimerism and minimal residual disease in patient with chronic myeloid leukemia after allogenic and syngenic bone marrow transplantation].
TLDR
The results of 8-year monitoring of chimerism and minimal residual disease validate application of molecular-cytogenetic methods for assessing transplant condition. Expand
Defect of stromal microenvironment in long term bone marrow cultures of patients with acute and chronic myelogenous leukemias.
TLDR
It is suggested that there may be a functional microenvironmental defect in CML and AML that may play a role in the pathogenesis of inhibition of normal hemopoiesis in these diseases. Expand
Front-Line High Dose Therapy with Following Autologous Stem Cell Transplantation (ASCT) for Follicular Lymphoma Patients
TLDR
This first experience of intensive therapy in FL in Russia demonstrates that ASCT as a front-line therapy leads to complete remission of FL among pts who have nonfavorable prognosis factors. Expand
Bone Marrow Multipotent Mesenchymal Stromal Cells in Patients with Diffuse Large B-Cell Lymphoma
TLDR
Despite the absence of proven involvement of the bone marrow, the properties of mesenchymalStromal cells, the components in the stromal microenvironment niche regulating hemopoiesis are altered in patients with diffuse large B-cell lymphoma. Expand
The Results of the Russian Clinical Trial of Mesenchymal Stromal Cells (MSCs) in Severe Neutropenic Patients (pts) with Septic Shock (SS) (RUMCESS trial)
TLDR
The significant increase in 28 days OS of the pts in CT+MCSs group was associated with SOFA score decrease, which was started in three days after onset of SS, but does not prevent death from sepsis-related organ dysfunction in long term. Expand
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