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Pseudomonas syringae pv. actinidiae: chemical control, resistance mechanisms and possible alternatives
This review summarizes all chemical compounds trialled so far against Psa and provides thoughts on the development of antimicrobial peptides as potential solutions for the future.
Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides
- S. Dissanayake, W. Denny, S. Gamage, V. Sarojini
- MedicineJournal of controlled release : official journal…
- 28 March 2017
This review focuses on peptides as carriers and targeting moieties in drug‐peptide covalent conjugates and summarizes the most recent literature examples where CPPs on their own or CPP's together with TTPs have been conjugated to anticancer drugs such as Doxorubicin, Methotrexate, Paclitaxel, Chlorambucil etc.
Preptin Analogues: Chemical Synthesis, Secondary Structure and Biological Studies
- C. Buchanan, Zhenzhen Peng, Aiko Cefre, V. Sarojini
- Chemistry, MedicineChemical biology & drug design
- 1 October 2013
Peptide hormones that modulate insulin secretion have been recognized to have therapeutic potential, with peptides such as amylin (pramlintide acetate, Symlin) and exendin‐4 (exenatide, Byetta) now…
A Multitargeted Approach: Organorhodium Anticancer Agent Based on Vorinostat as a Potent Histone Deacetylase Inhibitor
Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides.
- G. H. De Zoysa, A. Cameron, Veena Hegde, S. Raghothama, V. Sarojini
- Chemistry, MedicineJournal of medicinal chemistry
- 5 January 2015
We report on the first chemical syntheses and structure-activity analyses of the cyclic lipopeptide battacin which revealed that conjugation of a shorter fatty acid, 4-methyl-hexanoic acid, and…
Recent Developments in Antimicrobial-Peptide-Conjugated Gold Nanoparticles.
The following review discusses recent developments in the synthesis and antimicrobial activity studies of AMP-AuNPs.
Feasibility Study Exploring the Potential of Novel Battacin Lipopeptides as Antimicrobial Coatings.
- G. H. De Zoysa, V. Sarojini
- Materials Science, MedicineACS applied materials & interfaces
- 4 January 2017
Assessment of the in vitro antibacterial potency of the recently discovered lipopeptides from the battacin family indicate that they have the potential to be developed as promising antimicrobial coatings on medical implants.
A Safer and Convenient Synthesis of Sulfathiazole for Undergraduate Organic and Medicinal Chemistry Classes.
A safer method for the synthesis of the sulfonamide drug sulfathiazole, for undergraduate classes, is described. This method improves upon procedures currently followed in several undergraduate…
Cyclic Tetrapeptides from Nature and Design: A Review of Synthetic Methodologies, Structure, and Function.
- V. Sarojini, A. Cameron, Kyriakos G Varnava, W. Denny, G. Sanjayan
- Medicine, ChemistryChemical reviews
- 16 August 2019
The purpose of this review is to highlight the current state of affairs on naturally occurring and rationally designed cyclic tetrapeptides, including strategies investigated for their syntheses in the literature, the conformations adopted by these molecules, and specific examples of their function.
Effect of Antifreeze Peptide Pretreatment on Ice Crystal Size, Drip Loss, Texture, and Volatile Compounds of Frozen Carrots.
- Charles H. Z. Kong, N. Hamid, Tin-yin Liu, V. Sarojini
- Chemistry, MedicineJournal of agricultural and food chemistry
- 17 May 2016
The results prove the potential of these AFPs to preserve the above characteristics in frozen carrot samples and minimize drip loss and preserve color, structure, texture, and volatiles of frozen carrot.