Pseudomonas syringae pv. actinidiae: chemical control, resistance mechanisms and possible alternatives
- A. Cameron, V. Sarojini
- Biology
- 1 February 2014
This review summarizes all chemical compounds trialled so far against Psa and provides thoughts on the development of antimicrobial peptides as potential solutions for the future.
Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides
- S. Dissanayake, W. Denny, S. Gamage, V. Sarojini
- Biology, ChemistryJournal of Controlled Release
- 28 March 2017
Recent Developments in Antimicrobial-Peptide-Conjugated Gold Nanoparticles.
- Urawadee Rajchakit, V. Sarojini
- Biology, ChemistryBioconjugate chemistry
- 26 September 2017
The following review discusses recent developments in the synthesis and antimicrobial activity studies of AMP-AuNPs.
Cyclic-RGDyC functionalized liposomes for dual-targeting of tumor vasculature and cancer cells in glioblastoma: An in vitro boron neutron capture therapy study
- Weirong Kang, D. Svirskis, V. Sarojini, A. McGregor, J. Bevitt, Zimei Wu
- Biology, ChemistryOncoTarget
- 28 March 2017
The potential of a new dual-targeting strategy using c(RGDyC)-LP to improve boron neutron capture therapy for glioblastoma is demonstrated.
A Safer and Convenient Synthesis of Sulfathiazole for Undergraduate Organic and Medicinal Chemistry Classes.
- J. Boyle, Sandra Otty, V. Sarojini
- Chemistry
- 2012
A safer method for the synthesis of the sulfonamide drug sulfathiazole, for undergraduate classes, is described. This method improves upon procedures currently followed in several undergraduate…
Preptin Analogues: Chemical Synthesis, Secondary Structure and Biological Studies
- C. Buchanan, Zhenzhen Peng, Aiko Cefre, V. Sarojini
- Biology, ChemistryChemical Biology and Drug Design
- 1 October 2013
Peptide hormones that modulate insulin secretion have been recognized to have therapeutic potential, with peptides such as amylin (pramlintide acetate, Symlin) and exendin‐4 (exenatide, Byetta) now…
Molecular engineering of antimicrobial peptides: microbial targets, peptide motifs and translation opportunities
- P. Cardoso, Hugh D. Glossop, C. Valéry
- Biology, ChemistryBiophysical Reviews
- 21 January 2021
It is argued that basic research advances constitute a solid basis for promising industry translation of rationally designed synthetic peptide antimicrobials, not only as novel drugs against multidrug-resistant strains but also as components of emerging antimicrobial biomaterials.
Making Solid-Phase Peptide Synthesis Greener: A Review of the Literature.
- Kyriakos G Varnava, V. Sarojini
- Chemistry, BiologyChemistry - An Asian Journal
- 15 April 2019
This review summarizes the current literature on green solid-phase peptide synthesis successes and challenges encountered and concludes with suggestions for future research towards a simple and efficient green peptides synthesis protocol.
Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides.
- G. H. De Zoysa, A. Cameron, Veena Hegde, S. Raghothama, V. Sarojini
- Biology, ChemistryJournal of Medicinal Chemistry
- 5 January 2015
We report on the first chemical syntheses and structure-activity analyses of the cyclic lipopeptide battacin which revealed that conjugation of a shorter fatty acid, 4-methyl-hexanoic acid, and…
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