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Preferential attachment of peritoneal tumor metastases to omental immune aggregates and possible role of a unique vascular microenvironment in metastatic survival and growth.
Controlling metastases remains a critical problem in cancer biology. Within the peritoneal cavity, omental tissue is a common site for metastatic disease arising from intraperitoneal tumors; however,Expand
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Omental immune aggregates and tumor metastasis within the peritoneal cavity
The omentum, an important peritoneal tissue, is studded with a high number of immune aggregates, or “milky spots,” the number, function, and phenotype of which is largely unknown. We have analyzedExpand
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The Development of Macrophage-Mediated Cell Therapy to Improve Skeletal Muscle Function after Injury
Skeletal muscle regeneration following acute injury is a multi-step process involving complex changes in tissue microenvironment. Macrophages (MPs) are one of the key cell types involved inExpand
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Therapeutic potential of adipose-derived stem cells and macrophages for ischemic skeletal muscle repair.
AIM Progressive ischemia due to peripheral artery disease causes muscle damage and reduced strength of the lower extremities. Autologous cell therapy is an attractive treatment to restore perfusionExpand
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Fibrin‐based stem cell containing scaffold improves the dynamics of burn wound healing
For severe burn injuries, successful medical intervention is accomplished by rapidly and safely providing physical barriers that can cover damaged skin tissues, thereby preventing critical danger ofExpand
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Anti-inflammatory macrophages improve skeletal muscle recovery from ischemia-reperfusion.
The presence of macrophages (MPs) is essential for skeletal muscle to properly regenerate following injury. The aim of this study was the evaluation of MP profiles and their importance in skeletalExpand
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Recruitment and therapeutic application of macrophages in skeletal muscles after hind limb ischemia
Objective: Peripheral arterial disease can cause not only ischemia but also skeletal muscle damage. It has been known that macrophages (MPs) play an important role in coordinating muscle repair;Expand
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Controlled delivery of SDF-1α and IGF-1: CXCR4(+) cell recruitment and functional skeletal muscle recovery.
Therapeutic delivery of regeneration-promoting biological factors directly to the site of injury has demonstrated its efficacy in various injury models. Several reports describe improved tissueExpand
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Therapeutic assessment of mesenchymal stem cells delivered within a PEGylated fibrin gel following an ischemic injury.
The intent of the current study was to investigate the therapeutic contribution of MSCs to vascular regeneration and functional recovery of ischemic tissue. We used a rodent hind limb ischemia modelExpand
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