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Malaria transmission in urban sub-Saharan Africa.
TLDR
Evidence from past literature is presented to build a conceptual framework to begin to explain this heterogeneity in malaria transmission and the potential for malaria epidemics owing to decreasing levels of natural immunity being offset by negative impacts of urbanization on the larval ecology of anopheline mosquitoes. Expand
Gametocytemia and infectivity to mosquitoes of patients with uncomplicated Plasmodium falciparum malaria attacks treated with chloroquine or sulfadoxine plus pyrimethamine.
TLDR
Plasmodium falciparum gametocytes and their infectivity for mosquitoes were differentiated according to the drug used, its efficacy, and the duration of symptoms before treatment; they were not dependent on the density of asexual stages. Expand
Gametocytogenesis : the puberty of Plasmodium falciparum
TLDR
This review mainly focuses on the current knowledge on commitment to sexual development, gametocytogenesis and the evolutionary significance of various aspects of gametocyte biology. Expand
African apes as reservoirs of Plasmodium falciparum and the origin and diversification of the Laverania subgenus
TLDR
Two mitochondrial genes, one plastid gene, and one nuclear gene are investigated in blood samples from 12 chimpanzees and two gorillas from Cameroon and one lemur from Madagascar, suggesting that the falciparum + ape parasite cluster (Laverania clade) may have evolved from a parasite present in hosts not ancestral to the primates. Expand
Effect of gametocyte sex ratio on infectivity of Plasmodium falciparum to Anopheles gambiae.
TLDR
Insectary-reared Anopheles gambiae were experimentally fed with the blood of 90 naturally infected human volunteers carrying gametocytes of Plasmodium falciparum, raising interesting questions: why should higher sex ratios be more infective, and why is the observed population sex ratio lower than that which produces the greatest infectivity. Expand
Experimental infections of Anopheles gambiae with Plasmodium falciparum of naturally infected gametocyte carriers in Cameroon: factors influencing the infectivity to mosquitoes.
TLDR
Only gametocyte density was identified as a factor which determined the success and the level of mosquito infection in experimental infections of Anopheles gambiae with Plasmodium falciparum in Cameroon. Expand
Evolutionary forces on Anopheles: what makes a malaria vector?
TLDR
It is aimed to point out selection pressures exerted by Plasmodium on Anopheles to improve its own transmission and discuss how the parasite might shape the vector to its benefit. Expand
The evolutionary ecology of Plasmodium
TLDR
Exploration of the evolutionary ecology of Plasmodium will enable identification of key steps in the life cycle and highlight fruitful avenues of research for developing malaria control strategies. Expand
Chimpanzee Malaria Parasites Related to Plasmodium ovale in Africa
TLDR
This study provides the first evidence of possibility of natural cross-species exchange of P. ovale between humans and chimpanzees of the subspecies Pan t. Expand
Ecology of larval mosquitoes, with special reference to Anopheles arabiensis (Diptera: Culcidae) in market-garden wells in urban Dakar, Senegal.
TLDR
Results indicate that many contributing factors influence the ecology of the immature stages of An. Expand
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