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Acquired tumor cell radiation resistance at the treatment site is mediated through radiation-orchestrated intercellular communication.
PURPOSE Radiation resistance induced in cancer cells that survive after radiation therapy (RT) could be associated with increased radiation protection, limiting the therapeutic benefit of radiation.Expand
Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes
BackgroundDetermining the driving factors and molecular flow-through that define the switch from favorable to aggressive high-risk disease is critical to the betterment of neuroblastomaExpand
Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling
IntroductionHigh-risk neuroblastoma (HR-NB) presenting with hematogenous metastasis is one of the most difficult cancers to cure. Patient survival is poor. Aggressive tumors contain populations ofExpand
Nephroprotective effects of Colpomenia sinuosa (Derbes & Solier) against carbon tetrachloride induced kidney injury in Wistar rats
Abstract Objective To establish the protective effect of seaweed Colpomenia sinuosa against carbon tetra chloride (CCl 4 ) induced oxidative stress and resultant dysfunction of rat kidney. MethodsExpand
Abstract A4: Antagonistic effects of sulphated polysaccharides from Turbinaria conoides (J. Agardh) on tumor cell migration and angiogenesis
A4 Seaweeds are considered to be a rich source of biologically active substances like antioxidants, anti-viral, anti-inflammatory and anticoagulant agents. There are some evidences that seaweedsExpand
Abstract A5: Inhibition of tumor cell migration and angiogenesis by sulphated polysaccharides from Sargassum wightii (Greville)
Abstracts: Frontiers in Cancer Prevention Research 2008 A5 Seaweeds are potential renewable resources of the marine environment. They are low in fats but contain vitamins and bioactive compoundsExpand
Reorganization of metastamiRs in the evolution of metastatic aggressive neuroblastoma cells
BackgroundMetastamiRs have momentous clinical relevance and have been correlated with disease progression in many tumors. In this study, we identified neuroblastoma metastamiRs exploiting uniqueExpand
Erratum to: Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling
High-risk neuroblastoma (HR-NB) presenting with hematogenous metastasis is one of the most difficult cancers to cure. Patient survival is poor. Aggressive tumors contain populations of rapidlyExpand
Abscopal effect of low-LET γ-radiation mediated through Rel protein signal transduction in a mouse model of nontargeted radiation response
Ascertaining the ionizing radiation (IR)-induced bystander response and its preceding molecular regulation would increase our understanding of the mechanism of acute and delayed radiobiologicalExpand
RD3 loss dictates high-risk aggressive neuroblastoma and poor clinical outcomes
Clinical outcomes for high-risk neuroblastoma patients remains poor, with only 40–50% 5-Year overall survival (OS) and <10% long-term survival. The ongoing acquisition of genetic/molecularExpand
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