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Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A
TLDR
Available data from biomonitoring studies clearly indicate that the general population is exposed to BPA and is at risk from internal exposure to unconjugated BPA. Expand
Maternal bisphenol-A levels at delivery: a looming problem?
TLDR
This is the first study to document measurable levels of BPA in maternal blood of the US population and there was no correlation between BPA concentrations and gestational length or birth weight of offspring. Expand
Biomonitoring Studies Should Be Used by Regulatory Agencies to Assess Human Exposure Levels and Safety of Bisphenol A
TLDR
The reasons provided by the European Food Safety Authority (EFSA) BPA risk assessment panel for their conclusion that human exposures are negligible are compared with the conclusions reached by the other panels, with all panels having the same body of literature at their disposal. Expand
The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus: sex differences and effects of prenatal testosterone in sheep.
TLDR
Sex differences in kisspeptin in the arcuate nucleus, unlike that of dynorphin and neurokinin B, are not due solely to exposure to prenatal T, suggesting the existence of different critical periods for multiple peptides coexpressed within the same neuron. Expand
Characterization of endocrine events during the periestrous period in sheep after estrous synchronization with controlled internal drug release (CIDR) device.
TLDR
The data demonstrate that the CIDR device applied during the luteal phase effectively synchronizes estrus and results in a C IDR removal-to-surge interval of similar length to a natural follicular phase. Expand
Follicle-stimulating isohormones: characterization and physiological relevance.
TLDR
FSH exists as a family of isohormones which have been identified within the anterior pituitary, serum, and urine of several mammalian species, including man, andStructural differences in these isoforms alter their MCRs and biological and immunological potency relationships. Expand
Endocrine Alterations That Underlie Endotoxin-Induced Disruption of the Follicular Phase in Ewes1
TLDR
It is demonstrated that endotoxin invariably interrupts the preovulatory estradiol rise and delays or blocks the subsequent LH and FSH surges in the ewe. Expand
Bisphenol A and Chronic Disease Risk Factors in US Children
TLDR
Higher levels of urinary BPA were associated with a higher odds of obesity (BMI >95%) and abnormal waist circumference–to–height ratio and longitudinal analyses are needed to elucidate temporal relationships between BPA exposure and the development of obesity and chronic disease risk factors in children. Expand
Polycystic ovary syndrome and its developmental origins
TLDR
The prenatal testosterone (T)-treated adult female rhesus monkey is one animal model of polycystic ovary syndrome (PCOS) in women, with early prenatal T excess programming a permanent PCOS-like phenotype raising the possibility that T excess in human fetal development promotes PCOS in adulthood. Expand
Bisphenol A and Reproductive Health: Update of Experimental and Human Evidence, 2007–2013
TLDR
Based on reports that BPA impacts female reproduction and has the potential to affect male reproductive systems in humans and animals, BPA is a reproductive toxicant, which is considered an ovarian toxicant. Expand
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