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- Publications
- Influence
Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell.
- I. Goldman, N. Lichtenstein, V. Oliverio
- Medicine, Chemistry
- The Journal of biological chemistry
- 10 October 1968
Abstract Transport of methotrexate (4-amino-10-methylpteroyl-glutamic acid), a structural analogue of folic acid, was studied in L1210 mouse leukemia cells grown in tissue culture. Intracellular… Expand
The pharmacokinetics of [3H]‐vincristine in man
- R. Bender, M. C. Castle, D. A. Margileth, V. Oliverio
- Medicine
- Clinical pharmacology and therapeutics
- 1 October 1977
The pharmacokinetics, metabolism, and excretion of aromatically labeled tritiated vincristine (VCR) was examined in 4 patients. Clearance of radioactivity from the blood was triphasic with half‐life… Expand
The metabolic fate of tritiated methotrexate. I. Absorption, excretion, and distribution in mice, rats, dogs and monkeys.
- E. Henderson, R. Adamson, C. Denham, V. Oliverio
- Biology, Medicine
- Cancer research
- 1 August 1965
The absorption, excretion, distribution, metabolism, and serum protein binding of tritium-labeled methotrexate (MTX)[1][1] has been studied in a variety of laboratory mammals. In all species studied… Expand
The effect of organic acids on renal clearance of methotrexate in man
- D. Liegler, E. Henderson, M. Hahn, V. Oliverio
- Chemistry, Medicine
- Clinical pharmacology and therapeutics
- 1 November 1969
The renal clearance of the folic acid antagonist, methotrexate, was compared with that of inulin and para‐aminohippurate in 15 patients with disseminated malignancy. The clearance of methotrexate… Expand
The metabolic fate of tritiated methotrexate. II. Absorption and excretion in man.
- E. Henderson, R. Adamson, V. Oliverio
- Medicine
- Cancer research
- 1 August 1965
acid antagonist both iii the treatment of neoplastic dis eases such as acute lymphocytic leukemia of childhood and t.rophoblastic malignancies and in the investigation of a variety of immune… Expand
Distribution and excretion of (3H)vincristine in the rat and the dog.
- M. C. Castle, D. A. Margileth, V. Oliverio
- Medicine
- Cancer research
- 1 October 1976
The distribution and excretion of tritiated vincristine were studies in the rat and the dog. Biphasic curves for the disappearance of the drug from blood were found in both species, with an initial… Expand
The interaction of carcinogenic hydrocarbons with tissues. V. Some structural requirements for binding of 1,2,5,6-dibenzanthracene.
- V. Oliverio, C. Heidelberger
- Medicine
- Cancer research
- 1 October 1958
1. Sixteen C14-labeled derivatives of 1,2,5,6-dibenzanthracene (DBA), with substituent groups either in the 9,10-positions (L region) or on the phenanthrene double bonds (K regions), and… Expand
Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880).
- Jeffrey A. Gottlieb, A. Guarino, J. Call, V. Oliverio, J. B. Block
- Medicine
- Cancer chemotherapy reports
- 1 December 1970
TISSUE DISTRIBUTION OF FOLATE ANTAGONISTS
- V. Oliverio, D. Zaharko
- Biology, Medicine
- Annals of the New York Academy of Sciences
- 1 November 1971
During the past decade our laboratory has been engaged in studies of various aspects of the pharmacologic disposition of certain folate antagonists. Two of these agents, amethopterin (Methotrexate)… Expand
The physiologic disposition of dichloromethotrexate‐CI36 in man
- J. D. Davidson, V. Oliverio
- Biology, Medicine
- Clinical pharmacology and therapeutics
- 1 May 1965
Pharmacologic studies were made of the urinary and fecal excretion, blood levels, metabolism, and plasma binding of 3′,5′‐dichloromethotrexate (DCM), with a radioactive chlorine label, in patients… Expand