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How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans
Antenatal depression predicts depression in adolescent offspring: prospective longitudinal community-based study.
Sexual dysfunction in patients taking conventional antipsychotic medication
Conventional antipsychotic medications cause significant levels of sexual dysfunction and Clinicians should routinely enquire about sexual symptoms prior to the prescription of antipsychotics and on follow-up.
Vagus nerve stimulation for depression: efficacy and safety in a European study
VNS therapy was effective in reducing severity of depression; efficacy increased over time; reduction of symptom severity was significantly higher in the European sample than previously reported.
Antipsychotic Drugs: A New Risk Factor for Osteoporosis in Young Women With Schizophrenia?
The findings suggest that the high rates of osteoporosis associated with schizophrenia may result from hypogonadism secondary to antipsychotic-induced hyperprolactinemia, and that the prolactin-raising profile of antipsychotics drugs should be considered when choosing an antipsychosis drug.
Effects of long-term prolactin-raising antipsychotic medication on bone mineral density in patients with schizophrenia
- A. Meaney, Shubulade Smith, O. Howes, Moira O'Brien, R. Murray, V. O’Keane
- Medicine, PsychologyBritish Journal of Psychiatry
- 1 June 2004
Patients with schizophrenia on long-term prolactin-raising antipsychotic medication are at high risk of developing reduced bone mineral density as a consequence of hyperprolactinaemia-induced hypogonadism.
Two-Year Outcome of Vagus Nerve Stimulation in Treatment-Resistant Depression
- M. Bajbouj, A. Merkl, I. Heuser
- Psychology, MedicineJournal of clinical psychopharmacology
- 1 June 2010
The results of this 2-year open-label trial suggest a clinical response and a comparatively benign adverse effect profile among patients with treatment-resistant depression.
Bone mineral density changes over a year in young females with schizophrenia: Relationship to medication and endocrine variables
Increased pituitary-adrenal activation and shortened gestation in a sample of depressed pregnant women: a pilot study.
Antipsychotic-induced hyperprolactinaemia, hypogonadism and osteoporosis in the treatment of schizophrenia
- V. O’Keane
- Medicine, PsychologyJournal of psychopharmacology
- 1 March 2008
Preliminary findings from the studies suggest that active management of bone loss in those with antipsychotic-associated bone disease may halt or even reverse this process.