V. N. Carpio
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Noninvasive Tim-3 Messenger RNA Evaluation in Renal Transplant Recipients With Graft Dysfunction
- R. Manfro, E. C. Aquino-Dias, G. Joelsons, A. L. Nogare, V. N. Carpio, L. F. Gonçalves
- 27 December 2008
Background. Renal biopsies are usually needed to elucidate graft dysfunction. In this study, T-cell immunoglobulin domain, mucin domain mRNA expression in the peripheral blood leukocytes (PBL) and… Expand
Endothelin-1 and Endothelin A Receptor Immunoreactivity Is Increased in Patients with Diabetic Nephropathy
Background: Endothelin-1 (ET-1) is associated with progression of renal disease, acting as a vasoconstrictor and growth factor for mesangial cells. ET-1 and endothelin A receptor (ET-RA) might have a… Expand
Kidney injury molecule-1 expression in human kidney transplants with interstitial fibrosis and tubular atrophy
BackgroundKidney injury molecule-1 (KIM-1) is expressed in tubular epithelial cells after injury and may have a role in the development of renal graft fibrosis. In this study we evaluated the… Expand
Expression patterns of B cells in acute kidney transplant rejection.
- V. N. Carpio, I. Noronha, +7 authors F. J. Veronese
- Experimental and clinical transplantation…
- 1 October 2014
OBJECTIVES To evaluate B-cell expression patterns and association with function and survival in dysfunctional kidney allografts. MATERIALS AND METHODS There were 110 kidney transplant recipients… Expand
Clinical and pathological correlations of C4d immunostaining and its influence on the outcome of kidney transplant recipients.
- V. N. Carpio, C. Rech, +5 authors F. J. Veronese
- Jornal brasileiro de nefrologia : 'orgao oficial…
INTRODUCTION C4d is a marker of antibody-mediated rejection (ABMR) in kidney allografts, although cellular rejection also have C4d deposits. OBJECTIVE To correlate C4d expression with… Expand
FOXP3+ regulatory T cells: from suppression of rejection to induction of renal allograft tolerance.
- C. Dummer, V. N. Carpio, L. F. Gonçalves, R. Manfro, F. J. Veronese
- Medicine, Biology
- Transplant immunology
Naturally occurring and induced regulatory T cells (Tregs) can become hyporesponsive and anergic to antigen stimulation in autoimmune diseases and allograft rejection. The mechanisms of suppression… Expand
Analysis of FOXP3 Gene and Protein Expressions in Renal Allograft Biopsies and Their Association with Graft Outcomes
Background: The transcription factor FOXP3 is increased in acute renal rejection, but its influence on graft outcomes is unclear. This study correlated FOXP3 with dendritic cells and graft outcomes.… Expand
Evaluation of apoptosis in peripheral blood lymphocytes of renal transplant patients.
- V. N. Carpio, E. C. Aquino-Dias, T. Prochnow, R. Manfro, L. F. Gonçalves
- Transplantation proceedings
- 1 July 2006
The aim of this study was to evaluate the occurrence of apoptosis and the expression of FasL and IL-2 genes in apoptotic peripheral blood mononuclear cells (PBMC) at different posttransplant periods.… Expand
Noninvasive Molecular Biomarkers of Acute Antibody Mediated Rejection in Renal Transplant Patients: 473
Correlações clinico-patológicas da marcação de C4d e sua influência na evolução de receptores de transplante renal
INTRODUCTION: C4d is a marker of antibody-mediated rejection (ABMR) in kidney allografts, although cellular rejection also have C4d deposits. OBJECTIVE: To correlate C4d expression with… Expand