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- Publications
- Influence
Free Radical Intermediates in Sonodynamic Therapy
Abstract: Current understanding of the mechanism of sonodynamic action (i.e. the ultrasound‐dependent enhancement of the cytotoxic action of certain drugs ‐ sonosensitizers) with potential… Expand
Inhibition of rat and human cytochrome P4502E1 catalytic activity and reactive oxygen radical formation by nitric oxide.
- D. Gergel', V. Mišík, P. Riesz, A. Cederbaum
- Chemistry, Medicine
- Archives of biochemistry and biophysics
- 15 January 1997
Nitric oxide (NO) reacts with heme-containing enzymes, including certain isoforms of cytochrome P450. Cytochrome P4502E1 (CYP2E1) is induced by ethanol and plays an important role in the toxicity of… Expand
The potential pitfalls of using 1,1-diphenyl-2-picrylhydrazyl to characterize antioxidants in mixed water solvents
- A. Staško, V. Brezová, S. Biskupic, V. Mišík
- Chemistry, Medicine
- Free radical research
- 1 January 2007
Approaching living systems, aqueous solutions are appropriate to characterize antioxidants, whereas the frequently used standard 1,1-diphenyl-2-picrylhydrazyl (DPPH) is insoluble in water. Therefore,… Expand
Detection of alkoxyl and carbon-centered free radicals in coronary sinus blood from patients undergoing elective cardioplegia.
- A. Tortolani, S. Powell, V. Mišík, W. Weglicki, G. J. Pogo, J. Kramer
- Medicine
- Free radical biology & medicine
- 1 April 1993
Confirmation of the involvement of free radicals in postischemic injury in human heart has been elusive. The present study was performed to determine the presence of free radicals in coronary sinus… Expand
Magnesium-deficiency potentiates free radical production associated with postischemic injury to rat hearts: vitamin E affords protection.
- J. Kramer, V. Mišík, W. Weglicki
- Chemistry, Medicine
- Free radical biology & medicine
- 1 June 1994
Preexisting magnesium deficiency may alter the susceptibility of rat hearts to postischemic oxidative injury (free radicals). This was examined in rats maintained for 3 weeks on a magnesium-deficient… Expand
Lipoxygenase inhibition and antioxidant properties of protoberberine and aporphine alkaloids isolated from Mahonia aquifolium.
- V. Mišík, L. Bezáková, L. Máleková, D. Kostálová
- Chemistry, Medicine
- Planta medica
- 1 August 1995
Products of lipoxygenase metabolism play a role in the pathogenesis of psoriasis. Four protoberberine alkaloids, berberine, oxyberberine, jatrorrhizine, columbamine, and two aporphine alkaloids,… Expand
Lipid peroxidation of phosphatidylcholine liposomes depressed by the calcium channel blockers nifedipine and verapamil and by the antiarrhythmic-antihypoxic drug stobadine.
- K. Ondrias, V. Mišík, D. Gergèl, A. Staško
- Chemistry, Medicine
- Biochimica et biophysica acta
- 28 June 1989
Nifedipine, verapamil and stobadine were tested and compared with butylated hydroxytoluene (BHT) as possible free radical scavengers inhibiting lipid peroxidation in phosphatidylcholine liposomes.… Expand
Lipoxygenase inhibition and antioxidant properties of bisbenzylisoqunoline alkaloids isolated from Mahonia aquifolium.
- L. Bezáková, V. Mišík, L. Máleková, E. Svajdlenka, D. Kostálová
- Chemistry, Medicine
- Die Pharmazie
- 1 October 1996
Products of lipoxygenase metabolism are known to play a role in the pathogenesis of psoriasis. Six bisbenzylisoquinoline (BBIQ) alkaloids, oxyacanthine, armoline, baluchistine, berbamine, obamegine,… Expand
Redox intermediates of flavonoids and caffeic acid esters from propolis: an EPR spectroscopy and cyclic voltammetry study.
- P. Rapta, V. Mišík, A. Staško, I. Vrábel
- Chemistry, Medicine
- Free radical biology & medicine
- 1 May 1995
The redox properties of flavonoids: chrysin (1), tectochrysin (2), galangin (3), isalpinin (4), pinostrobin (5), pinobanksin (6), pinobanksin-3-acetate (7), and of caffeic acid ester (8) and… Expand
Increased Cytotoxicity of 3-Morpholinosydnonimine to HepG2 Cells in the Presence of Superoxide Dismutase
- D. Gergel', V. Mišík, K. Ondrias, A. Cederbaum
- Chemistry, Medicine
- The Journal of Biological Chemistry
- 8 September 1995
3-Morpholinosydnonimine (SIN-1) is widely used to generate nitric oxide (NO) and superoxide radical (O). The effect of SOD on the toxicity of SIN-1 is complex, depending on what is the ultimate… Expand