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Gα13 Mediates a Signal That Is Essential for Proliferation and Survival of Thymocyte Progenitors
- V. McNeil Coffield, Whitney S. Helms, Q. Jiang, L. Su
- BiologyThe Journal of experimental medicine
- 15 November 2004
Overexpression of the antiapoptotic gene Bcl2 rescued the defect in DN3 cells and partially rescued T cell development and demonstrated that Gα13-mediated signaling is necessary in early thymocyte proliferation and survival.