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Tracing European founder lineages in the Near Eastern mtDNA pool.
TLDR
There has been substantial back-migration into the Near East, there was a founder effect or bottleneck associated with the Last Glacial Maximum, 20,000 years ago, and a way to account for multiple dispersals of common sequence types is suggested. Expand
Correcting for purifying selection: an improved human mitochondrial molecular clock.
TLDR
A modest effect of purifying selection on the mtDNA coding region is confirmed and an improved molecular clock for dating human mtDNA is proposed, based on a worldwide phylogeny of > 2000 complete mtDNA genomes and calibrating against recent evidence for the divergence time of humans and chimpanzees. Expand
The emerging tree of West Eurasian mtDNAs: a synthesis of control-region sequences and RFLPs.
TLDR
It is shown that the main indigenous North African cluster is a sister group to the most ancient cluster of European mtDNAs, from which it diverged approximately 50,000 years ago. Expand
Natural selection shaped regional mtDNA variation in humans
TLDR
It is concluded that selection may have played a role in shaping human regional mtDNA variation and that one of the selective influences was climate. Expand
The making of the African mtDNA landscape.
TLDR
The results suggest that the southeast Bantu speakers have a composite origin on the maternal line of descent, with approximately 44% of lineages deriving from West Africa, approximately 21% from either West or Central Africa, Approximately 30% from East Africa, and approximately 5% from southern African Khoisan-speaking groups. Expand
Single, Rapid Coastal Settlement of Asia Revealed by Analysis of Complete Mitochondrial Genomes
TLDR
It is shown that mitochondrial DNA variation in isolated “relict” populations in southeast Asia supports the view that there was only a single dispersal from Africa, most likely via a southern coastal route, through India and onward into southeast Asia and Australasia. Expand
Phylogeography of mitochondrial DNA in western Europe
TLDR
A cladistic notation for mitochondrial variation is described and analysis is expanded upon to present a more detailed portrait of the European mitochondrial record, suggesting that most extant mitochondrial sequences in western Europe have a local ancestry in the Early Upper Palaeolithic. Expand
Paleolithic and neolithic lineages in the European mitochondrial gene pool.
TLDR
It follows that the major extant lineages throughout Europe predate the Neolithic expansion and that the spread of agriculture was a substantially indigenous development accompanied by only a relatively minor component of contemporary Middle Eastern agriculturalists. Expand
A mitochondrial stratigraphy for island southeast Asia.
TLDR
It is demonstrated that mitochondrial DNA diversity in the region is extremely high and includes a large number of indigenous clades, suggesting that, if an agriculturalist migration did take place in ISEA, it was demographically minor, at least with regard to the involvement of women. Expand
A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes.
TLDR
Phylogeographic analyses suggest that a large component of the present Khoisan gene pool is eastern African in origin and that Asia was the source of a back migration to sub-Saharan Africa. Expand
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