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Structural brain abnormalities in major depressive disorder: a selective review of recent MRI studies.
BACKGROUND While there is evidence to suggest that major depressive disorder (MDD) is associated with structural brain abnormalities, the precise nature of these abnormalities remains unclear. AIMSExpand
The anticipation and outcome phases of reward and loss processing: A neuroimaging meta‐analysis of the monetary incentive delay task
The processing of rewards and losses are crucial to everyday functioning. Considerable interest has been attached to investigating the anticipation and outcome phases of reward and loss processing,Expand
Effect of long-term cannabis use on axonal fibre connectivity.
Cannabis use typically begins during adolescence and early adulthood, a period when cannabinoid receptors are still abundant in white matter pathways across the brain. However, few studies to dateExpand
Functional Connectivity in Brain Networks Underlying Cognitive Control in Chronic Cannabis Users
The long-term effect of regular cannabis use on brain function underlying cognitive control remains equivocal. Cognitive control abilities are thought to have a major role in everyday functioning,Expand
Increased pituitary volume in schizophrenia spectrum disorders
While hypothalamic-pituitary-adrenal (HPA) axis hyperactivity has been implicated in psychotic disorders, previous magnetic resonance imaging (MRI) studies of the pituitary gland volume inExpand
The Role of Cannabinoids in Neuroanatomic Alterations in Cannabis Users
The past few decades have seen a marked change in the composition of commonly smoked cannabis. These changes primarily involve an increase of the psychoactive compound ∆(9)-tetrahydrocannabinol (THC)Expand
Structural MRI Findings in Long-Term Cannabis Users: What Do We Know?
In animal studies, tetrahydrocannabinol (THC) has been found to affect brain morphology, particularly within areas rich in cannabinoid receptors (e.g., hippocampus, cerebral cortex). While cannabisExpand
Gross morphological brain changes with chronic, heavy cannabis use.
We investigated the morphology of multiple brain regions in a rare sample of 15 very heavy cannabis users with minimal psychiatric comorbidity or significant exposure to other substances (comparedExpand
The association between regular cannabis exposure and alterations of human brain morphology: an updated review of the literature.
Cannabis is the most widely used illicit drug worldwide, though it is unclear whether its regular use is associated with persistent alterations in brain morphology. This review examines evidence fromExpand
Volumetric MRI study of the insular cortex in individuals with current and past major depression.
BACKGROUND Functional neuroimaging studies have implicated the insular cortex in emotional processing, including the evaluation of one's own emotion, as well as in the neurobiology of majorExpand