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- Influence
In vitro cyanide degradation by Serretia marcescens RL2b
Detoxification of cyanide compounds using biological systems is gaining much attention due to various advantages over the traditional physical and chemical methods. In present study, a cyanide… Expand
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Indirect resolution of enantiomers of penicillamine by TLC and HPLC using Marfey's reagent and its variants.
- R. Bhushan, H. Brueckner, V. Kumar
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 1 October 2007
TLC and HPLC methods were developed for indirect chiral separation of penicillamine (3,3-dimethylcysteine) enantiomers after derivatization with Marfey's reagent (FDNP-Ala-NH(2)) and two of its… Expand
Polysubstituted 2-aminoimidazoles as anti-biofilm and antiproliferative agents: Discovery of potent lead.
- Rupinder Kaur Gill, V. Kumar, Stijn C.A. Robijns, H. Steenackers, Erik V. Van der Eycken, Jitender Bariwal
- Chemistry, Medicine
- European journal of medicinal chemistry
- 29 September 2017
Most of the human bacterial infections are associated with the biofilm formation and the natural tolerance of biofilms to antibiotics challenges treatment. Because of their low immunity, cancer… Expand
Multi‐Component Solvent‐Free versus Stepwise Solvent Mediated Reactions: Regiospecific Formation of 6‐Trifluoromethyl and 4‐Trifluoromethyl‐1H‐pyrazolo[3,4‐b]pyridines.
- R. Aggarwal, V. Kumar, A. Bansal, D. Sanz, R. M. Claramunt
- Chemistry
- 13 November 2012
The regiospecific synthesis of 6-fluoromethyl-pyrazolopyridines (IV) is achieved in high yields via a three-component reaction under solvent-free conditions.
Synthesis, physico-chemical and thermal characteristics of seven and ten coordinated complexes of trivalent lanthanides derived from 4[N-(cinnamalidene)amino]antipyrine semicarbazone and diphenyl…
- R. Agarwal, B. Prakash, V. Kumar, A. Aslam Khan
- Chemistry
- 1 March 2007
In present studies a new series of twenty four complexes of seven and ten coordinated compounds derived from 4[Ncinnamalidene) amino]antipyrine semicarbazone (CAAPS) as primary ligand and diphenyl… Expand
Indirect enantioseparation of alpha-amino acids by reversed-phase liquid chromatography using new chiral derivatizing reagents synthesized from s-triazine chloride.
- R. Bhushan, V. Kumar
- Chemistry, Medicine
- Journal of chromatography. A
- 1 August 2008
Ten chiral dichloro- and monochloro-s-triazines were prepared by the nucleophilic displacement of chlorine atom(s) in s-triazine chloride and its 6-methoxy derivative with different amino acid… Expand
Indirect resolution of baclofen enantiomers from pharmaceutical dosage form by reversed-phase liquid chromatography after derivatization with Marfey's reagent and its structural variants.
- R. Bhushan, V. Kumar
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 1 August 2008
A high-performance liquid chromatographic (HPLC) method was developed for chiral assay of baclofen enantiomers in pharmaceutical formulations using an indirect approach. Baclofen enantiomers were… Expand
Indirect TLC Resolution of Amino Acid Enantiomers After Derivatization with Marfey’’s Reagent and its Chiral Variants
- R. Bhushan, H. Brückner, V. Kumar, D. Gupta
- Chemistry
- JPC – Journal of Planar Chromatography – Modern…
- 1 June 2007
A simple and rapid method has been established for indirect separation of the optical isomers of seventeen dl amino acids by reversed-phase and normal-phase TLC. Amino acids derivatized with… Expand
Chromatographic separation of enantiomers of non-protein α-amino acids after derivatization with Marfey’s reagent and its four variants
- R. Bhushan, V. Kumar, Shivani Tanwar
- Chemistry, Medicine
- Amino Acids
- 1 March 2009
Some non-protein α-amino acids were derivatized with 1-fluoro-2,4-dinitrophenyl-5-l-alaninamide (Marfey’s reagent, MR, FDNP-l-Ala-NH2,) and four of its structural variants FDNP-l-Phe-NH2,… Expand
Copper(II) chloride mediated synthesis and DNA photocleavage activity of 1-aryl/heteroaryl-4-substituted-1,2,4-triazolo[4,3-a]quinoxalines.
- R. Aggarwal, Garima Sumran, V. Kumar, Ashwani Mittal
- Chemistry, Medicine
- European journal of medicinal chemistry
- 1 December 2011
A new class of photonucleases, 1-aryl/heteroaryl-4-substituted-1,2,4-triazolo[4,3-a]quinoxalines (4) was synthesized in a facile and efficient manner via copper(II) chloride mediated oxidative… Expand