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Impact of CYP2E1 genotype in renal cell and urothelial cancer patients.
Glycose aminoglycane excretion and concentration in the urine of patients with frequently recurrent calcium-oxalate lithiasis prior to and following Diclofenac-Na therapy
TLDR
Elevation of the high-molecular inhibitor potential in the urine results in reduced risk of calcium-oxalate lithogenesis, which may explain the therapeutic successe of nonsteroidal anti-inflammatory drugs in the treatment of therapy resistent calcium- oxalates lithiasis.
Influence of magnesium on the absorption and excretion of calcium and oxalate ions.
TLDR
The calcium oxalate crystallization rates in the 5-or 7-hour urines reveal a behavior parallel to that of the oxalic acid excretion profile, and new aspects of magnesium effects must be discussed.
Analysis of point mutation in exon 2 of CYP2E1 gene in renal cell/urothelial cancer patients in comparison with control population.
TLDR
A screening method based on the polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) could not detect any point mutation in any of the 158 renal cell/urothelial cancer patients or the 150 controls, which might indicate a lack of association between this CYP2E polymorphisms (CYP2E1*2).
CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.
TLDR
The results show that CYP2E1 genotype cannot predict risk for renal cell/urothelial cancer in the population from 2 different regions in Germany.
Real Indications for Adrenalectomy in Renal Cell Carcinoma
TLDR
Adrenalectomy should only be performed if there is radiographic evidence of metastases in the adrenal gland or adrenal infiltration by a large upper-pole tumor is possible and macroscopically normal adrenal glands should not be removed during tumor nephrectomy because the need and benefit of routine adrenalectomy are extremely limited.
Laparoscopic adrenalectomy in urological centres – the experience of the German Laparoscopic Working Group
TLDR
Study Type – Practice patterns (retrospective cohort) – practice patterns ( RETROspective cohort).
Genetic alterations in metastatic renal cell carcinoma detected by comparative genomic hybridization: correlation with clinical and histological data.
TLDR
Genetic changes leading to metastases occurred early in tumorigenesis of metastatic tumors, which could be useful for predicting prognosis.
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