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Therapeutic Delivery of Cyclin A2 Induces Myocardial Regeneration and Enhances Cardiac Function in Ischemic Heart Failure
TLDR
This approach of inducing endogenous myocardial regeneration provides proof-of-concept evidence that cyclin A2 may ultimately serve as an efficient, alternative therapy for heart failure.
Fat grafting's past, present, and future: why adipose tissue is emerging as a critical link to the advancement of regenerative medicine.
TLDR
The objectives of this review are to discuss the clinical applications of fat grafting, describe the cellular biology of fat and the optimization offat graft preparation, illustrate the significance of adipose-derived stem cells and the potentiality of fat cells, and explore the current and future frontiers of the study ofFat grafting.
Squamosal Suture Synostosis: A Cause of Atypical Skull Asymmetry
TLDR
Patients with isolated squamosal synostosis often suffered from a deformity that was mild in severity and tended to improve with time, however, when occurring in the setting of other forms of craniosynostosis, the deformity was often progressive, and transcranial surgery was frequently required.
Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression
TLDR
Total myocardial apelin and APJ receptor levels increase in compensation for ischemic cardiomyopathy, as demonstrated by western blot and enzyme immunoassay analysis.
Placental Growth Factor Provides a Novel Local Angiogenic Therapy for Ischemic Cardiomyopathy
TLDR
Intramyocardial delivery of PlGF following a large myocardial infarction enhanced border zone angiogenesis, attenuated adverse ventricular remodeling, and preserved cardiac function may be useful as an adjunct or alternative to standard revascularization techniques in patients with ischemic heart failure.
Minimally invasive aortic valve papillary fibroelastoma resection.
TLDR
A minimally invasive approach to the resection of aortic valve papillary fibroelastoma to decrease operative trauma, reduce postoperative bleeding, decrease pulmonary complications, and expedite recovery from surgery is demonstrated.
Creatine phosphate administration preserves myocardial function in a model of off-pump coronary revascularization.
TLDR
A strategy of intravenous high-energy phosphate administration successfully prevented ischemic ventricular dysfunction in a rodent model of OPCAB.
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