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Building neural representations of habits.
TLDR
Large and widely distributed changes in the neuronal activity patterns occurred in the sensorimotor striatum during behavioral acquisition, culminating in task-related activity emphasizing the beginning and end of the automatized procedure. Expand
Involvement of extrapyramidal motor mechanisms in the suppression of locomotor activity by antipsychotic drugs: A comparison between the effects produced by pre- and post-synaptic inhibition of
TLDR
Using exploratory locomotor activity as an index of limbic forebrain DA functions and treadmill locomotion and catalepsy as indices of extrapyramidal DA functions, the DA autoreceptor agonists, in contrast to the postsynaptic antagonist, show a difference in the doses required to produce these effects. Expand
Stimulation of 5-HT1A and 5-HT1B receptors in brain regions and its effects on male rat sexual behaviour.
TLDR
The results would suggest that at least some of the 5-HT1A receptors involved in the facilitation of male sexual behaviour are located postsynaptically in limbic brain areas that regulate maleSexual behaviour. Expand
Facilitation and inhibition of male rat ejaculatory behaviour by the respective 5‐HT1A and 5‐HT1B receptor agonists 8‐OH‐DPAT and anpirtoline, as evidenced by use of the corresponding new and
TLDR
The present results demonstrate opposite effects, facilitation and inhibition, of male rat ejaculatory behaviour by stimulation of 5‐HT1A and 5‐ HT1B receptors, respectively, suggesting that the SSRI‐induced inhibition of male ejaculatory dysfunction is due to 5-HT1B receptor stimulation. Expand
Effects of raclopride on exploratory locomotor activity, treadmill locomotion, conditioned avoidance behaviour and catalepsy in rats: behavioural profile comparisons between raclopride, haloperidol
TLDR
Raclopride is more potent than preclamol in suppressing treadmill locomotion, conditioned avoidance behaviour and catalepsy, indicating less propensity to produce severe extrapyramidal side effects. Expand
High doses of oxytocin cause sedation and low doses cause an anxiolytic-like effect in male rats
TLDR
A spectrum of effects caused by oxytocin was similar to that of midazolam but different from that induced by raclopride, and the behavior gradually returned to normal within 24 h. Expand
Region-selective inhibition of male rat sexual behavior and motor performance by localized forebrain 5-HT injections: a comparison with effects produced by 8-OH-DPAT
TLDR
An inhibitory role of ventral forebrain 5-HT in the mediation of male rat sexual behavior is suggested and 8-OH-DPAT of the male rat copulatory performance after median raphe injections is probably due to stimulation of 5- HT1A autoreceptors in this brainstem region. Expand
Effects of local application of 5-HT and 8-OH-DPAT into the dorsal and median raphe nuclei on motor activity in the rat
TLDR
Different roles for serotonergic mechanisms in the DR and MR in the mediation of spontaneous motor activity in the rat are demonstrated, and also a possible specific role for 5-HT1 receptors is suggested. Expand
Evidence for specific involvement of 5-HT1A and 5-HT2A/C receptors in the expression of patterns of spontaneous motor activity of the rat.
TLDR
The 5-HT1A and the 5- HT2A/C receptor agonists 8-hydroxy-2-(di-n-propylamino)tetralin and (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) produced a similar stereotyped forward locomotion in rats, although the intensity of the behavioral change was considerably less with DOI. Expand
Effects of 8-OH-DPAT on motor activity in the rat
TLDR
The administration of 8-OH-DPAT to rats produced a dose-dependent suppression of spontaneous locomotor activity in an open field arena and vertical activity ("rearing") was more sensitive to the treatment than horizontal activity ("locomotion"), both in terms of potency and efficacy. Expand
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