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- Publications
- Influence
A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA.
- K. Bucholz, R. Cadoret, +6 authors M. Schuckit
- Psychology, Medicine
- Journal of studies on alcohol
- 1 March 1994
Within- and cross-center test-retest studies were conducted to study the reliability of a new, semistructured, comprehensive, polydiagnostic psychiatric interview being used in a multisite genetic… Expand
Variants in nicotinic receptors and risk for nicotine dependence.
- L. Bierut, J. Stitzel, +30 authors A. Goate
- Biology, Medicine
- The American journal of psychiatry
- 1 September 2008
OBJECTIVE
A recent study provisionally identified numerous genetic variants as risk factors for the transition from smoking to the development of nicotine dependence, including an amino acid change… Expand
Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.
- H. Edenberg, D. Dick, +17 authors H. Begleiter
- Biology, Medicine
- American journal of human genetics
- 1 April 2004
Alcoholism is a complex disease with both genetic and environmental risk factors. To identify genes that affect the risk for alcoholism, we systematically ascertained and carefully assessed… Expand
Genome-wide search for genes affecting the risk for alcohol dependence.
- T. Reich, H. Edenberg, +20 authors H. Begleiter
- Biology, Medicine
- American journal of medical genetics
- 8 May 1998
Alcohol dependence is a leading cause of morbidity and premature death. Several lines of evidence suggest a substantial genetic component to the risk for alcoholism: sibs of alcoholic probands have a… Expand
A genome-wide association study of alcohol dependence
- L. Bierut, A. Agrawal, +36 authors J. Rice
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 2 March 2010
Excessive alcohol consumption is one of the leading causes of preventable death in the United States. Approximately 14% of those who use alcohol meet criteria during their lifetime for alcohol… Expand
Types of alcoholics, I. Evidence for an empirically derived typology based on indicators of vulnerability and severity.
- T. Babor, M. Hofmann, +4 authors B. Rounsaville
- Psychology, Medicine
- Archives of general psychiatry
- 1 August 1992
An empirical clustering technique was applied to data obtained from 321 male and female alcoholics to identify homogeneous subtypes having discriminative and predictive validity. The clustering… Expand
Comparison of direct interview and family history diagnoses of alcohol dependence.
- J. Rice, T. Reich, +7 authors H. Begleiter
- Psychology, Medicine
- Alcoholism, clinical and experimental research
- 1 August 1995
Using data from The Collaborative Study on the Genetics of Alcoholism, we compare direct interview diagnoses of alcohol dependence to those obtained by history from family members. Using a… Expand
Allelic and haplotypic association of GABRA2 with alcohol dependence
- J. Covault, J. Gelernter, V. Hesselbrock, M. Nellissery, H. Kranzler
- Biology, Medicine
- American journal of medical genetics. Part B…
- 15 August 2004
Alcohol dependence is a highly prevalent disorder that is associated with serious morbidity and mortality. Because the GABAA neurotransmitter receptor is an important mediator for several behavioral… Expand
Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism.
- L. Bierut, S. Dinwiddie, +6 authors T. Reich
- Psychology, Medicine
- Archives of general psychiatry
- 1 November 1998
BACKGROUND
Alcoholism and substance dependence frequently co-occur. Accordingly, we evaluated the familial transmission of alcohol, marijuana, and cocaine dependence and habitual smoking in the… Expand
A validity study of the SSAGA--a comparison with the SCAN.
- M. Hesselbrock, C. Easton, K. Bucholz, M. Schuckit, V. Hesselbrock
- Psychology, Medicine
- Addiction
- 1 September 1999
OBJECTIVE
This study examined the concurrent diagnostic validity of the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) across alcohol and drug dependencies, major depression,… Expand