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Multicomponent Analysis of the Differential Induction of Secondary Metabolite Profiles in Fungal Endophytes
Small molecule histone deacetylase (HDAC) and DNA methyltransferase (DNMT) inhibitors are commonly used to perturb the production of fungal metabolites leading to the induction of the expression ofExpand
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Graminin B, a furanone from the fungus Paraconiothyrium sp.
Members of the furanone structural class of natural oxygenated heterocycles have been reported from fungi of the genera Cephalosporium (for example, gregatins and graminin A), Aspergillus (huaspenoneExpand
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Assessing the effects of adsorptive polymeric resin additions on fungal secondary metabolite chemical diversity
Adsorptive polymeric resins have been occasionally described to enhance the production of specific secondary metabolites (SMs) of interest. Methods that induce the expression of new chemical entitiesExpand
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Hypoxylon pulicicidum sp. nov. (Ascomycota, Xylariales), a Pantropical Insecticide-Producing Endophyte
Background Nodulisporic acids (NAs) are indole diterpene fungal metabolites exhibiting potent systemic efficacy against blood-feeding arthropods, e.g., bedbugs, fleas and ticks, via binding toExpand
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MDN-0104, an antiplasmodial betaine lipid from Heterospora chenopodii.
Bioassay-guided fractionation of the crude fermentation extract of Heterospora chenopodii led to the isolation of a novel monoacylglyceryltrimethylhomoserine (1). The structure of this new betaineExpand
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Cyclic colisporifungin and linear cavinafungins, antifungal lipopeptides isolated from Colispora cavincola.
Colisporifungin (1), a cyclic depsilipopeptide structurally related to the aselacins, and cavinafungins A and B, two linear peptides, were isolated from liquid culture broths of the hithertoExpand
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Isolation and structural elucidation of cyclic tetrapeptides from Onychocola sclerotica.
Three new cyclic tetrapeptides (1-3) have been isolated from the crude fermentation extract of Onychocola sclerotica. The planar structures of 1-3 were elucidated by detailed spectroscopic analysesExpand
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Biodiversity and chemotaxonomy of Preussia isolates from the Iberian Peninsula
This work documents 32 new Preussia isolates from the Iberian Peninsula, including endophytic and saprobic strains. The morphological study of the teleomorphs and anamorphs was combined with aExpand
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Hormonemate Derivatives from Dothiora sp., an Endophytic Fungus.
A search for cytotoxic agents from cultures of the endophytic fungus Dothiora sp., isolated from the endemic plant Launaea arborescens, led to the isolation of six new compounds structurally relatedExpand
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Cercospora sp. as a source of anti-aging polyketides targeting 26S proteasome and scale-up production in submerged bioreactor.
From a large screening of microbial extracts for the discovery of proteasome modulating natural products, the fungal strain Cercospora sp. (CF-223709) was selected as the most promising for furtherExpand
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