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- Publications
- Influence
Structure of the Mechanosensitive Channel MscS Embedded in the Membrane Bilayer.
- T. Rasmussen, V. Flegler, A. Rasmussen, B. Böttcher
- Biology, Medicine
- Journal of molecular biology
- 7 July 2019
Since life has emerged, gradients of osmolytes over the cell membrane cause pressure changes in the cell and require tight regulation to prevent cell rupture. The mechanosensitive channel of small… Expand
Capabilities of the Falcon III detector for single-particle structure determination
- B. Song, Julian Lenhart, V. Flegler, C. Makbul, T. Rasmussen, B. Böttcher
- Chemistry
- 1 August 2019
Abstract Direct electron detectors are an essential asset for the resolution revolution in electron cryo microscopy of biological objects. The direct detectors provide two modes of data acquisition;… Expand
Think beyond the core: The impact of the hydrophilic corona on the drug solubilization using polymer micelles.
- M. Haider, Michael M. Lübtow, +6 authors R. Luxenhofer
- Materials Science, Medicine
- ACS applied materials & interfaces
- 7 May 2020
Polymeric micelles are typically characterized as core-shell structures. The hydrophobic core is considered as depot for hydrophobic molecules and the corona forming block acts as stabilizing and… Expand
Capabilities of the Falcon III detector for single-particle structure determination.
- B. Song, Julian Lenhart, V. Flegler, C. Makbul, T. Rasmussen, B. Böttcher
- Medicine
- Ultramicroscopy
- 2019
Direct electron detectors are an essential asset for the resolution revolution in electron cryo microscopy of biological objects. The direct detectors provide two modes of data acquisition; the… Expand
Inverse Thermogelation of Aqueous Triblock Copolymer Solutions into Macroporous Shear-Thinning 3D Printable Inks.
- Lukas Hahn, M. Maier, +10 authors R. Luxenhofer
- Materials Science, Medicine
- ACS applied materials & interfaces
- 6 March 2020
Amphiphilic block copolymers that undergo (reversible) physical gelation in aqueous media are of great interest in different areas including drug delivery, tissue engineering, regenerative medicine,… Expand
small conductance mechanosensitive channel YbiO
- V. Flegler, A. Rasmussen, +6 authors B. Böttcher
- Materials Science
- 18 November 2020
YnaI in an open-like conformation
- V. Flegler, A. Rasmussen, +6 authors B. Boettcher
- Chemistry
- 25 November 2020
The MscS-like channel YnaI has a gating mechanism based on flexible pore helices
- V. Flegler, A. Rasmussen, +6 authors B. Böttcher
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences
- 4 November 2020
Significance Many biological processes are based on mechanosensitive channels which are stimulated by mechanical forces. In cell-walled organisms, the large family of MscS-like channels is extremely… Expand