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Comparative study of natural antioxidants - curcumin, resveratrol and melatonin - in cadmium-induced oxidative damage in mice.
TLDR
It is demonstrated that curcumin, resveratrol and melatonin pre-treatment effectively protect against cadmium-induced lipid peroxidation and ameliorate the adverse effect of Cadmium on antioxidant status without any reduction in tissue Cd burden. Expand
Mechanisms of the apoptotic and necrotic actions of trimethyltin in cerebellar granule cells.
TLDR
It was concluded that low concentrations of trimethyltin cause apoptotic cell death in which oxidative signaling is an important event, and higher concentrations of TMT initiate necrotic death, which involves both an oxidative and a non-oxidative component. Expand
The effect of curcumin on cadmium-induced oxidative damage and trace elements level in the liver of rats and mice.
TLDR
In rats and mice, the level of Cd-induced lipid peroxidation was significantly lowered by curcumin pre-treatment, and was accompanied by significant increase of glutathione (GSH) level in both C d-treated and Cd plusCurcumin-treated group, which did not cause systematic alterations in trace element status. Expand
Kojic acid and its derivatives: history and present state of art.
TLDR
Kojic acid derivatives are promising compounds that might advantageously be used in human and/or veterinary medicine and also in preparation of new, even more biologically active preparations. Expand
Long lasting cadmium intake is associated with reduction of insulin receptors in rat adipocytes
TLDR
Diminished insulin receptors in adipocytes could account for diabetogenic effect of long lasting cadmium intake in drinking tap water, and no differences in the content of GLUT4 in crude plasma membranes of adipose tissue were observed. Expand
Protective effect of manganese in cadmium-induced hepatic oxidative damage, changes in cadmium distribution and trace elements level in mice
TLDR
Manganese(II) pretreatment attenuated the interference of cadmium with Ca homeostasis, the alteration in Zn and Cu levels remained mostly unaffected and the effect of manganese may result from a different metallothionein induction in particular organs. Expand
Effect of melatonin, curcumin, quercetin, and resveratrol on acute ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative damage in rats
TLDR
The results indicate that the pretreatment with natural antioxidants, curcumin, melatonin, quercetin, and resveratrol, significantly and equally suppressed lipid peroxidation induced by Fe-NTA but had no effect on other markers of FeNTA nephrotoxicity and iron deposition in kidneys. Expand
Effect of cadmium chelating agents on organ cadmium and trace element levels in mice.
TLDR
In experiments performed on male mice, the mobilizing effects of repeated administration of the carbodithioate analogue BLDTC and CaDTPA on cadmium deposits in the liver, kidneys, brain and testes were compared and confirmedBLDTC to be one of the most effective Cadmium mobilizing agents. Expand
Trace Elements Status in Selenium-Deficient Rats—Interaction with Cadmium
TLDR
Selenium-deficient rats of both genders showed significantly lower accumulation of cadmium in the liver, compared to Se-adequate rats, and Cadmium supplementation increased zinc and decreased iron hepatic level, regardless of Se status and decreased copper concentration in Se- inadequate rats. Expand
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