V. Dorneanu

Publications94
h-index8
Citations311
Highly Influential Citations12
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New data referring to chemistry of Withania somnifera species.
The withanolides are a category of active principles of great pharmacodynamic importance with regard to our own research. We obtained alkaloids, 18 fatty acids, beta-sitesterol, polyphenols and…
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THE CHEMICAL PROFILE OF ESSENTIAL OILS OBTAINED FROM FENNEL FRUITS (FOENICULUM VULGARE MILL.)
Fennel (Foeniculum vulgare Mill., Apiaceae) is a well-known aromatic and medicinal plant. Essential oils obtained by hydrodistillation from fresh ripe fruits of fennel collected during three…
Cyclosporine bioavailability of two physically different oral formulations.
TLDR
The outcome does not support free and full interchangeability in chronic stable graft recipients of the two products studied, unless validated clinical and laboratory conversion protocols for each kind of organ transplantation are enforce.
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[Pharmacognostic research of some species of Achillea. Note 1. Volatile oils analysis].
TLDR
The hydrodistilled essential oil yields from the dried flower heads of A. collina are established and the results obtained for a mixture of some species differ from literature data in the presence of bisabolol, which have not been found so far in Achillea species.
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A TURBIDIMETRIC METHOD FOR THE ASSAY OF MELOXICAM USING MOLYBDOPHOSPHORIC ACID
A turbidimetric method was developed for the assay of meloxicam using molybdophosphoric acid in hydrochloric acid medium. The reaction product showed an absorbance maximum at 342 nm. The optimum…
Schiff bis bases: analytical reagents. II. Spectrophotometric determination of manganese from pharmaceutical forms.
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Possible involvement of L-arginine-nitric oxide pathway in the modulation of stress-induced analgesia.
TLDR
In the pretreated animals with L-NAME a progressive increase of latency time was obtained and the increased latencies induced by acute immobilization appeared significantly potentiated, offering new indirect evidence in favour of the modulatory role of NO in the thermoalgesic sensitivity and stress induced analgesia.
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Spectrometric determination of total antioxidant activity in chlorpromazine radical cation - ascorbic acid system.
TLDR
The spectrometric method has a good linearity, precision, accuracy, and is easy to use for evaluation of antioxidant action of different products and has the advantage of using a radical involved in redox processes in the body.
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VALIDATION OF AN ANALYTICAL METHOD BASED ON HIGH PERFORMANCE LIQUID CHROMATOGRAPHY FOR DETERMINATION OF LORATADINE IN PHARMACEUTICAL PREPARATIONS AND BIOLOGICAL ENVIRONMENTS
TLDR
The high-performance liquid chromatography method was successfully applied to synthesis process control and determination of loratadine as substance and pharmaceutical preparations and validated in terms of linearity, accuracy, selectivity, precision, limit of detection and limit of quantification.
[Membrane-selective electrode for atropine assay].
TLDR
This electrode was used with good results for quantitative assay by direct potentiometry and potentiometric titration of atropine sulphate from pharmaceutical formulations, and has a linear response in the concentration range of 10(-2)-10(-5) M atropin sulphate.
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