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Monanchocidin: a new apoptosis-inducing polycyclic guanidine alkaloid from the marine sponge Monanchora pulchra.
TLDR
Compound 1 shows pro-apoptotic and cytoxic activities and the structure of 1 was assigned on the basis of detailed analysis of 1D and 2D NMR spectra, mass spectrometry, and results of chemical transformations.
Echinamines A and B, first aminated hydroxynaphthazarins from the sea urchin Scaphechinus mirabilis.
Two new spinochromes, echinamines A (1) and B (2), were isolated from the sea urchin Scaphechinus mirabilis. Compounds 1 and 2 represent the first examples of natural polyhydroxynaphthazarins with a
Synthesis of ginsenoside Rg3, a minor constituent of Ginseng radix.
Meroterpenoids from the alga-derived fungi Penicillium thomii Maire and Penicillium lividum Westling.
TLDR
Ten new austalide meroterpenoids (1-10) were isolated from the alga-derived fungi and exhibited significant inhibitory activity against endo-1,3-β-D-glucanase from a crystalline stalk of the marine mollusk Pseudocardium sachalinensis.
Synthesis of 3β,20S-dihydroxydammar-24-en-12-one 3,20-di-O-β-D-glucopyranoside (chikusetsusaponin-LT8), a glycoside from Panax japonicus
A method for preparative production of 3β,20S-dihydroxydammar-24-en-12-one 3,20-di-O-β-D-glucopyranoside (1), a glycoside from Panax japonicus, chikusetsusaponin-LT8 was developed. Chemical
Monanchocidins B-E: polycyclic guanidine alkaloids with potent antileukemic activities from the sponge Monanchora pulchra.
TLDR
Compounds 1-5 show potent cytotoxic activities against HL-60 human leukemia cells with IC50 values of 540, 200, 110, 830, and 650 nM, respectively.
Spongiadioxins A and B, two new polybrominated dibenzo-p-dioxins from an Australian marine sponge Dysidea dendyi.
TLDR
Two new cytotoxic tetrabromodibenzo-p-dioxins were isolated from an Australian marine sponge Dysidea dendyi and established by 1D and 2D NMR spectroscopy, X-ray analysis, and synthesis of the methyl ether of spongiadioxin B from diphenyl ether isolated from dysidea herbacea.
Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim.
TLDR
These isoflavonoids, possessing a hepatoprotective activity, were stably produced by the A-18 calli for prolonged periods of observation.
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