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Enzymology and compartmentation of polymethylated flavonol glucosides in chrysosplenium americanum
Abstract The enzymatic synthesis of polymethylated flavonol glucosides in Chrysosplenium americanum is catalysed by a number of distinct, position-specific O -methyltransferases and OExpand
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An α-carbonic anhydrase from the thermophilic bacterium Sulphurihydrogenibium azorense is the fastest enzyme known for the CO2 hydration reaction.
We report the biochemical characterization of a new carbonic anhydrase (CA, EC 4.2.1.1), named SazCA, identified by translated genome inspection in Sulfurihydrogenibium azorense, a thermophilicExpand
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Association of β-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathy
Purpose Increased sympathetic nervous system activation via the β-adrenergic pathway influences the evolution of idiopathic dilated cardiomyopathy. We assessed the effects of β-adrenergic receptorExpand
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Testing primordial black holes as dark matter with LISA
The idea that primordial black holes (PBHs) can comprise most of the dark matter of the universe has recently reacquired a lot of momentum. Observational constraints, however, rule out thisExpand
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Inhibition of prostaglandin synthesis reduces hyperthermic reactions induced by hypocretin-1/orexin A
This experiment tested (i) the effect of orexin A injected into a lateral cerebral ventricle on sympathetic and thermogenic activity and (ii) the involvement of prostaglandins in these phenomena. TheExpand
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Olanzapine blocks the sympathetic and hyperthermic reactions due to cerebral injection of orexin A
Since experiments regarding a possible relation between olanzapine and orexin A has been scarcely reported in international literature, this experiment tested the effect of olanzapine on theExpand
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Characterization and Properties of a New Thermoactive and Thermostable Carbonic Anhydrase
A new carbonic anhydrase was isolated and characterized from the thermophilic bacterium Sulfurihydrogenibium sp. YO3AOP1. The encoding gene was cloned and expressed in Escherichia coli and theExpand
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Conformation-dependent inactivation of tryptophan decarboxylase from Catharanthus roseus
Catharanthus roseus tryptophan decarboxylase (TDC) was irreversibly inactivated in crude extracts and in purified form by incubation of the enzyme at 37 °C. The half-life of inactivation of TDC was...
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The Ineludible non-Gaussianity of the Primordial Black Hole Abundance
We study the formation of primordial black holes when they are generated by the collapse of large overdensities in the early universe. Since the density contrast is related to the comoving curvatureExpand
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Parodoxical effect of orexin A: hypophagia induced by hyperthermia
This experiment tested the effect of the sympathetic and thermogenic activation induced by orexin A on eating behavior. The food intake, firing rate (FR) of the sympathetic nerves to interscapularExpand
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