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Antibacterial activity of alkaloids from Sida acuta
TLDR
The gas chromatography-mass spectrometry analysis of the same alkaloids led to the identification of cryptolepine and quindoline as the major components of S. acuta from Burkina Faso. Expand
Traditional medicine: past, present and future research and development prospects and integration in the National Health System of Cameroon.
TLDR
An insight is given into the strategic plan and road map set up by the Government of Cameroon for the organisational framework and research platform for the practice and development of TM, and the global partnership involving the management of TM in the country. Expand
Drug-induced expansion and differentiation of V gamma 9V delta 2 T cells in vivo: the role of exogenous IL-2.
TLDR
The functional characteristics of Vgamma9Vdelta2 T cells from Macaca fascicularis (cynomolgus monkey) are very similar to those from Homo sapiens and may be relevant for designing novel (or modifying current) immunotherapeutic trials with nitrogen-containing bisphosphonate or pyrophosphomonoester drugs. Expand
Antioxidant and Anti-Inflammatory Activities of Extracts from Cassia alata, Eleusine indica, Eremomastax speciosa, Carica papaya and Polyscias fulva Medicinal Plants Collected in Cameroon
TLDR
Ethanol extracts showed strong antioxidant properties against both hydrogen peroxide and superoxide anion, and may contribute to the value for these plants in traditional medicine and in general medical practice. Expand
Abusive use of antibiotics in poultry farming in Cameroon and the public health implications
TLDR
The need for better management of antibiotic use to control sources of food contamination and reduce health risks associated with the presence of residues and the development of resistant pathogens is implied by further legislation and enforcement of regulations on food hygiene and use of antibiotics. Expand
Reference Values of Lymphocyte Subsets in Healthy, HIV-Negative Children in Cameroon
TLDR
The immunological profile for children aged from birth through 6 years in Cameroon is reported and lymphocyte subset reference values among children from Cameroon differ from reported values in Caucasian and some African populations. Expand
P2X(7) purinergic receptors and extracellular ATP mediate apoptosis of human monocytes/macrophages infected with Mycobacterium tuberculosis reducing the intracellular bacterial viability.
TLDR
The data indicate a role of P2X(7) purinergic receptors in MTB-induced M/M apoptosis, suggesting the existence of an autocrine/paracrine loop leading to apoptosis of infected M/ M and the feasible protective role of ATP-triggered cell death in tuberculosis. Expand
Implementation of HIV early infant diagnosis and HIV type 1 RNA viral load determination on dried blood spots in Cameroon: challenges and propositions.
TLDR
The findings from this study indicate that the use of DBS provides a powerful tool for perinatal screening programs, improvement on the testing algorithm, and follow-up during treatment, and should be scaled up to the entire nation. Expand
Characterization of drug resistance mutations in naïve and ART‐treated patients infected with HIV‐1 in Yaounde, Cameroon
TLDR
The high level of drug resistance observed in the cohort is alarming because this occurred as a result of only few years of treatment, and adherence to therapy, adequate education of physicians, and the appropriate use of genotypic resistance assay are critical points of intervention for the improvement of patient care. Expand
Molecular epidemiology of HIV type 1 CRF02_AG in Cameroon and African patients living in Italy.
TLDR
The evaluation of the spread of CRF02_AG may provide significant insight about the future dynamics of the Italian and European epidemic, as well as multiple independent introductions in the Italian population. Expand
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