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A method for making group inferences from functional MRI data using independent component analysis
A novel approach for drawing group inferences using ICA of fMRI data is introduced, and its application to a simple visual paradigm that alternately stimulates the left or right visual field is presented.
Tracking whole-brain connectivity dynamics in the resting state.
- E. Allen, E. Damaraju, S. Plis, E. Erhardt, T. Eichele, V. Calhoun
- PsychologyCerebral cortex
- 1 March 2014
It is suggested that the study of time-varying aspects of FC can unveil flexibility in the functional coordination between different neural systems, and that the exploitation of these dynamics in further investigations may improve the understanding of behavioral shifts and adaptive processes.
A Baseline for the Multivariate Comparison of Resting-State Networks
A multivariate analytic approach that optimizes sensitivity and reduces unnecessary testing is introduced and is demonstrated by identifying the effects of age and gender on the resting-state networks of 603 healthy adolescents and adults.
A review of group ICA for fMRI data and ICA for joint inference of imaging, genetic, and ERP data
A method for functional network connectivity among spatially independent resting-state components in schizophrenia
Aberrant "default mode" functional connectivity in schizophrenia.
- A. G. Garrity, G. Pearlson, K. McKiernan, D. Lloyd, K. Kiehl, V. Calhoun
- Psychology, MedicineThe American journal of psychiatry
- 1 March 2007
Schizophrenia is associated with altered temporal frequency and spatial location of the default mode network, and this network may be under- or overmodulated by key regions, including the anterior and posterior cingulate cortex.
Spatial and temporal independent component analysis of functional MRI data containing a pair of task‐related waveforms
A careful examination of some of the assumptions behind ICA methodologies is reported, examples of when applying ICA would provide difficult‐to‐interpret results, and suggestions for applying I CA to fMRI data especially when more than one task‐related component is present in the data are offered.
Selective changes of resting-state networks in individuals at risk for Alzheimer's disease
- C. Sorg, V. Riedl, A. Wohlschläger
- Psychology, BiologyProceedings of the National Academy of Sciences
- 20 November 2007
This work analyzes functional and structural MRI data from healthy elderly and patients with amnestic mild cognitive impairment and concludes that in individuals at risk for AD, a specific subset of RSNs is altered, likely representing effects of ongoing early neurodegeneration.
Dynamic functional connectivity: Promise, issues, and interpretations
Alterations in Memory Networks in Mild Cognitive Impairment and Alzheimer's Disease: An Independent Component Analysis
These data may also provide functional evidence of the interaction between neocortical and medial temporal lobe pathology in early AD, and suggest that loss of functional integrity of the hippocampal-based memory systems is directly related to alterations of neural activity in parietal regions seen over the course of MCI and AD.