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Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation
Vesiclepedia is a community-annotated compendium of molecular data on extracellular vesicles.
Nuclear Envelope Budding Enables Large Ribonucleoprotein Particle Export during Synaptic Wnt Signaling
Localized protein synthesis requires assembly and transport of translationally silenced ribonucleoprotein particles (RNPs), some of which are exceptionally large. Where in the cell such large RNP… Expand
Torsin mediates primary envelopment of large ribonucleoprotein granules at the nuclear envelope.
A previously unrecognized mechanism through which large ribonucleoprotein (megaRNP) granules exit the nucleus is by budding through the nuclear envelope (NE). This mechanism is akin to the nuclear… Expand
Integration of a Retrograde Signal during Synapse Formation by Glia-Secreted TGF-β Ligand
- Yuly Fuentes-Medel, J. Ashley, R. Barria, R. Maloney, M. Freeman, V. Budnik
- Biology, Medicine
- Current Biology
- 9 October 2012
Glial cells are crucial regulators of synapse formation, elimination, and plasticity [1, 2]. In vitro studies have begun to identify glial-derived synaptogenic factors , but neuron-glia signaling… Expand
Extracellular vesicles round off communication in the nervous system
Functional neural competence and integrity require interactive exchanges among sensory and motor neurons, interneurons and glial cells. Recent studies have attributed some of the tasks needed for… Expand
Glial Wingless/Wnt Regulates Glutamate Receptor Clustering and Synaptic Physiology at the Drosophila Neuromuscular Junction
- Kimberly S. Kerr, Yuly Fuentes-Medel, +7 authors V. Budnik
- Medicine, Biology
- The Journal of Neuroscience
- 19 February 2014
Glial cells are emerging as important regulators of synapse formation, maturation, and plasticity through the release of secreted signaling molecules. Here we use chromatin immunoprecipitation along… Expand
Introduction on the use of the Drosophila embryonic/larval neuromuscular junction as a model system to study synapse development and function, and a brief summary of pathfinding and target…
Publisher Summary This chapter reviews the history of the system and many of the methods that are used to study a variety of problems, from pathfinding to synapse plasticity in Drosophila. The… Expand
A critical step for postsynaptic F‐actin organization: Regulation of Baz/Par‐3 localization by aPKC and PTEN
- Preethi Ramachandran, R. Barria, J. Ashley, V. Budnik
- Medicine, Biology
- Developmental neurobiology
- 1 August 2009
Actin remodeling has emerged as a critical process during synapse development and plasticity. Thus, understanding the regulatory mechanisms controlling actin organization at synapses is exceedingly… Expand
Plasticity and second messengers during synapse development.
Publisher Summary This chapter outlines the experimental paradigms for the study of plasticity at the neuromuscular junction (NMJ) and discusses the cellular parameters are to be altered by… Expand
Dissection of Drosophila larval body-wall muscles.
Cold Spring Harb Protoc Preethi Ramachandran and Vivian Budnik Larval Body-Wall Muscles Drosophila Dissection of Service Email Alerting click here. Receive free email alerts when new articles cite… Expand