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Antiproliferative activity of pristimerin isolated from Maytenus ilicifolia (Celastraceae) in human HL-60 cells.
Pristimerin has been shown to be cytotoxic to several cancer cell lines. In the present work, the cytotoxicity of pristimerin was evaluated in human tumor cell lines and in human peripheral bloodExpand
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Kaurane and trachylobane diterpenes from Xylopia aethiopica
Abstract Phytochemical investigation of Xylopia aethiopica (Annonaceae) has resulted in the isolation of two novel diterpenes, 15-oxo-(-)-trachyloban-19-oic acid and (-)-kaur-15-en-17-al-19-oic acid.Expand
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Composition and antifungal activity of essential oils from Piper aduncum, Piper arboreum and Piper tuberculatum
The composition of essential oils from leaves, stems and fruits of Piper aduncum, P. arboreum and P. tuberculatum was examined by means of GC-MS and antifungal assay. There was a predominance ofExpand
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Acetylated DNA-damaging clerodane diterpenes from Casearia sylvestris.
In addition to the known diterpene casearin G (1), two new clerodane diterpene casearins type, casearin S (2) and casearin T (3), were isolated from an acetylated bioactive CH(2)Cl(2)/MeOH extractExpand
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A chromene and prenylated benzoic acid from Piper aduncum.
In addition to nerolidol, 2',6'-dihydroxy-4'-methoxydihydrochalcone, methyl 2,2-dimethyl-8-(3'-methyl-2'-butenyl)-2H-1-chromene-6-carboxylate, methyl 2,2-dimethyl-2H-1-chromene-6-carboxylate andExpand
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Produtos naturais: atualidade, desafios e perspectivas
This article offers an overview on the historical facts and the recent state of art of Chemistry of Natural Products which, in the course of 25 years of SBQ, have led to the present development ofExpand
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Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
Two alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, andExpand
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Phytochemical investigations on three Brazilian Lauraceae species from the Cerrado region of Sao Paulo State, Ocotea corymbosa (Meins) Mez., O. elegans Mez. and Persea pyrifolia Nees & Mart. ex NeesExpand
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A new neolignan and antioxidant phenols from Nectandra grandiflora
The EtOH crude extract from the leaves of Nectandra grandiflora collected in the Atlantic Forest, Brazil, showed antioxidant activity towards b-carotene in a TLC assay. The bioassay-guidedExpand
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Antifungal amides from Piper hispidum and Piper tuberculatum.
Piper hispidum and Piper tuberculatum accumulate amides bearing isobutyl, pyrrolidine, dihydropyridone and piperidine moieties. The isolation and characterization of several representatives includingExpand
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