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A new and rapid colorimetric determination of acetylcholinesterase activity.
TLDR
A photometric method for determining acetylcholinesterase activity of tissue extracts, homogenates, cell suspensions, etc., has been described and Kinetic constants determined by this system for erythrocyte eholinesterases are presented. Expand
Modulation by citrate of glycolytic oscillations in skeletal muscle extracts.
TLDR
Advantages of oscillatory behavior of glycolysis in the regulation of carbohydrate utilization and the maintenance of a high [ATP]/[ADP] ratio are demonstrated. Expand
Effect of denervation on the distribution and developmental transition of phosphoglycerate mutase and creatine phosphokinase isozymes in rat muscles of different fiber-type composition.
TLDR
In 5-day-old rats, denervation prevented the developmental increase of PGM and CK activity in all three muscles, and prevented the normal decrease in the relative amounts of the MB and BB isozymes of both enzymes which occur during postnatal muscle development. Expand
Distribution and developmental transition of phosphoglycerate mutase and creatine phosphokinase isozymes in rat muscles of different fiber-type composition.
TLDR
It is concluded that whereas phosphoglycerate mutase and creatine phosphokinase type-B subunits are present at similar levels in both type I and type II muscle fibers, phosphoglycersate mut enzyme type-M subunits exhibit much higher levels in type II fibers. Expand
Regulation of muscle phosphofructokinase by physiological concentrations of bisphosphorylated hexoses: effect of alkalinization.
TLDR
It is suggested that the hexose bisphosphates could play a significant role in the initial burst of the glycolytic flux during muscle contraction, when an alkaline pH shift is produced. Expand
Identification of guanine and adenine nucleotides as activators of glucose-1,6-bisphosphatase activity from rat skeletal muscle.
TLDR
The results of assays in vitro suggest that adenine nucleotides could be physiological modulators of glucose-1,6-bisphosphatase activity during muscle contraction. Expand
Oscillatory synthesis of glucose 1,6-bisphosphate and frequency modulation of glycolytic oscillations in skeletal muscle extracts.
TLDR
It is concluded that autocatalytic activation of phosphofructokinase by fructose-1,6-P2, but not by glucose-1+, may nevertheless play a role in facilitating the initiation of the oscillations and in modulating their frequency. Expand
Myofibril-bound muscle phosphofructokinase is less sensitive to inhibition by ATP than the free enzyme, but retains its sensitivity to stimulation by bisphosphorylated hexoses.
TLDR
It is suggested that the binding of phosphofructokinase to myofibrils in combination with increasing glucose 1,6-bisphosphate concentration could be important in the enhancement of the glycolytic flux that takes place during muscle contraction. Expand
Activation of muscle phosphofructokinase by alpha-glucose 1,6-bisphosphate and fructose 2,6-bisphosphate is differently affected by other allosteric effectors and by pH.
Citrate, ATP and AMP affect similarly the activation of muscle phosphofructokinase by alpha-glucose 1,6-bisphosphate and fructose 1,6-bisphosphate, but they affect differently its activation byExpand
Glucose 1,6-bisphosphate and fructose 2,6-bisphosphate in muscle from healthy humans and chronic alcoholic patients.
TLDR
Chronic alcohol intake produces an increase in the concentration of glucose 1,6-bisphosphate and fructose 2, 6-bisPhosphate in human muscle before the first sign of myopathy appears, which could contribute to the decline in skeletal muscle performance. Expand