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Screening for novel plant sources of prenyloxyanthraquinones: Senna alexandrina Mill. and Aloe vera (L.) Burm. F.
- F. Epifano, S. Fiorito, M. Locatelli, V. A. Taddeo, S. Genovese
- Medicine, BiologyNatural product research
- 17 January 2015
The extraction and HPLC separation of madagascin and 3-geranyloxyemodine from dried leaves and fruits of Senna alexandrina Mill and Aloe vera are described.
Comparison of different extraction methods and HPLC quantification of prenylated and unprenylated phenylpropanoids in raw Italian propolis.
- V. A. Taddeo, F. Epifano, S. Fiorito, S. Genovese
- Medicine, ChemistryJournal of pharmaceutical and biomedical analysis
- 10 September 2016
"Classic" maceration in general performed better than ultrasound-assisted one in determining the presence of selected prenylated and unprenylated phenylpropanoids in Italian raw propolis after having been extracted with different methodologies.
Inhibition of nitric oxide production by natural oxyprenylated coumarins and alkaloids in RAW 264.7 cells
Abstract A series of naturally occurring 3,3-dimethylallyloxy- and geranyloxycoumarins and alkaloids were chemically synthesized and tested as anti-inflammatory agents for their inhibitory effects on…
An Example of a Novel Efficient Plant Extraction Technique: Electromagnetic Induction Heating
- F. Epifano, Francesca Preziuso, V. A. Taddeo, S. Fiorito, S. Genovese
- Medicine, ChemistryMolecules
- 1 November 2018
A simple and easy to handle extraction procedure based on the use of electromagnetic induction heating for emodin quantification from an hydroalcoholic extract of rhizome of Rheum palmatum (Chinese rhubarb) was described.
A green deep eutectic solvent dispersive liquid-liquid micro-extraction (DES-DLLME) for the UHPLC-PDA determination of oxyprenylated phenylpropanoids in olive, soy, peanuts, corn, and sunflower oil.
This is the first time that eco-friendly solvents are used for the extraction of oxyprenylated phenylpropanoids and the corresponding extract analyzed with ultra high performance liquid chromatography with photodiode array detection.
Auraptene and Other Prenyloxyphenylpropanoids Suppress Microglial Activation and Dopaminergic Neuronal Cell Death in a Lipopolysaccharide-Induced Model of Parkinson’s Disease
- S. Okuyama, Tomoki Semba, +7 authors Y. Furukawa
- MedicineInternational journal of molecular sciences
- 1 October 2016
Whether AUR, 7-IP, and GOFA suppress microglial activation and protect against dopaminergic neuronal cell death in the SN is investigated and it is successfully showed that these prenyloxyphenylpropanoids exhibited prospective abilities, suggesting the potential of these compounds as neuroprotective agents for patients with PD.
Quantification of biologically active O‐prenylated and unprenylated phenylpropanoids in dill (Anethum graveolens), anise (Pimpinella anisum), and wild celery (Angelica archangelica)
- V. A. Taddeo, S. Genovese, P. Medina, Roberta Palmisano, F. Epifano, S. Fiorito
- Chemistry, MedicineJournal of pharmaceutical and biomedical analysis
- 5 February 2017
The experimental approach demonstrated to be efficient for the simultaneous identification and quantitation of the above mentioned prenyloxyphenylpropanoids in the title plant species, that is reported herein for the first time in the literature.
A green chemical synthesis of coumarin-3-carboxylic and cinnamic acids using crop-derived products and waste waters as solvents
Abstract Crop-derived products, like juices obtained from edible fruits and vegetables, and waste waters deriving from agricultural and industrial processing have been recently exploited to…
Microwave-assisted synthesis of coumarin-3-carboxylic acids under ytterbium triflate catalysis
Abstract Coumarin-3-carboxylic acids represent a class of natural occurring and semi-synthetic products with valuable reported pharmacological activities. In this Letter a new and improved method for…