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Clinical efficacy, safety, and pharmacokinetics of indapamide in renal impairment.
TLDR
Results obtained from single-blind, placebo-controlled studies indicate that indapamide is a safe and effective agent to use in lowering the blood pressure of hypertensive patients with normal renal function, those with various degrees of renal impairment, and those who are undergoing long-term maintenance hemodialysis. Expand
A comparison of danaparoid and warfarin for prophylaxis against deep vein thrombosis after total hip replacement: The Danaparoid Hip Arthroplasty Investigators Group.
TLDR
It is demonstrated that danaparoid is more effective than warfarin in preventing deep vein thrombosis following hip replacement surgery and the preoperative administration of danaproid does not increase surgical blood loss compared withwarfarin. Expand
Use of enoxaparin, a low-molecular-weight heparin, and unfractionated heparin for the prevention of deep venous thrombosis after elective hip replacement. A clinical trial comparing efficacy and
TLDR
A randomized, parallel-group, open-label clinical trial (the physicians, patients, and staff were not blinded with regard to the regimen that had been used) to compare the safety and efficacy of enoxaparin and unfractionated heparin for the prevention of deep venous thrombosis after elective hip replacement. Expand
Evaluation of the effectiveness of two support surfaces following myocutaneous flap surgery.
TLDR
A clinical trial compared the effectiveness of the ROHO dry-floatation mattress to that of the Clinitron bed and indicated that post-operative patients were effectively treated on either support surface. Expand
Danaparoid in the Prevention of Thromboembolic Complications
TLDR
Based on the efficacy and safety data reviewed, danaparoid should be considered one of the drugs of choice for the prevention of thromboembolic complications in patients undergoing orthopedic hip procedures and the drug ofchoice for the management of any patient with heparin-induced thrombocytopenia who requires anticoagulant therapy. Expand
Drug Information Center Network: Need, Effectiveness, and Cost Justification
TLDR
The data indicate that in Tennessee, there is a need for providing drug and toxicology information; pharmacists perceive their role to be providers of drug information as well as drugs; the DIC plays an integral and necessary role as a back-up information resource and in teaching, service, research, and continuing education programs. Expand
Review of Diclofenac and Evaluation of its Place in Therapy as a Nonsteroidal Antiinflammatory Agent
TLDR
Clinical trials suggest that diclofenac has a favorable side-effect profile, excellent patient tolerability, and a lower patient dropout rate when compared with aspirin and other NSAID. Expand
Leuprolide: A Gonadotropin-Releasing Hormone Analog for the Palliative Treatment of Prostatic Cancer
TLDR
Leuprolide has been found effective in the palliative treatment of advanced cases of prostatic cancer and is not associated with the cardiovascular and thromboembolic toxicity seen with conventional diethylstilbestrol therapy. Expand
Terfenadine, a Nonsedating Antihistamine
TLDR
The lack of CNS depression and anticholinergic effects, and the long duration of action that allows twice-a-day dosing make terfenadine an attractive alternative to other antihistamines. Expand
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