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OBJECTIVE Fibroblast growth factor 21 (FGF21) shows great potential for the treatment of obesity and type 2 diabetes, as its long-acting analogue reduces body weight and improves lipid profiles of participants in clinical studies; however, the intracellular mechanisms mediating these effects are poorly understood. AMP-activated protein kinase (AMPK) is an(More)
Let ρ(s) be a fixed infinitely differentiable function defined on R+ = [0,∞) having the properties: (i) ρ(s) ≥ 0, (ii) ρ(s) = 0 for s ≥ 1, and (iii) Rm δn(x)dx = 1 where δn(x) = cmnmρ(n2r2) and cm is the constant satisfying (iii). We overcome difficulties arising from computing ∇lδn and express this regular sequence by two mutual recursions and use a Java(More)
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