V. Ya. Bordzilovskii

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Due to a favorable combination of physicochemical, biological, and pharmaceutical properties, polyurethanes and related compounds have proved to be the most appropriate polymeric base for macromolecular therapeutic systems (MTS) [ 1 -3 ] . For example, a foamed polyurethane (FPU)based MTS, containing the immobilized drug dioxidine and certain proteolytic(More)
The wide use of proteinase based drugs in medicine is limited because of the instability of most of these enzymatic preparations [l]. The probability of inactivation can be reduced to a certain extent by immobilizing the enzymes on a polymeric matrix [2]. At the same time, the presence of enzymatic components in the known macromolecular therapeutic systems(More)
In recent years investigations [1] directed toward the creation of new-generation drugs (one Of the elements of which is a polymer fragment) for prolonged continuous administration of drugs according to a set program, i.e., the so-called macromolecular therapeutic systems (MTS), have been intensively developed. The most suitable and interesting class of(More)
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