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Journals and Conferences
On the basis of examining 55 patients with Gilles de la Tourette's syndrome psychic disturbances thought to be not characteristic of the disease before are described. A suggestion on nosological independence of the disease, and on possible participation of the cholinergic systems in the pathogenesis of the ailment is raised. The results of various therapy… (More)
On the basis of a clinical study of 162 patients presenting with ticotic hyperkineses as one of their major symptoms of the disease, the conclusion is drawn about the staged development of the syndrome in subclinical forms. Differential-diagnostic signs allowing the differentiation of Tourette's syndrome with simple and neurotic tics are outlined.
A total of 150 patients with Tourette's syndrome were treated by different neurotropic drugs. A conclusion has been made that pimozide (orap) is the drug of choice in the treatment of this syndrome. In cases of drug resistance the author recommends the use of cholinolytic comatose therapy. Long-acting neuroleptics have also been effective.
The duration of the R-R cardiointerval (CI) in 13 patients with Tourette's syndrome (TS) aged 9 to 17 years proved to be significantly (+17%; p less than 0.001) longer than in 27 patients of the same age with other neuropsychiatric diagnoses (temporal epilepsy, schizophrenia, neurosis, residual organics) and when compared with the normal values for the… (More)
The manifestations of Tourette's disease, represent the combination of neurologic and psychopathologic symptomatology. The patients show such manifestations as tics and obsessions while both groups of symptoms are fairly resistant to conservative therapy. The authors describe a case where stereotaxic cryodestruction of the ventrolateral nucleus of the… (More)